LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | XMD11-85h | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11087 | 11217 | 0.9884 | 0.9915 |
MCF 10A | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10893 | 11217 | 0.9711 | 0.9785 |
MCF 10A | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1694 | 10639 | 11217 | 0.9486 | 0.9616 |
MCF 10A | XMD11-85h | 10 | uM | LJP6 | 72 | hr | 1694 | 9171 | 11217 | 0.8177 | 0.8576 |
MCF 10A | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 10283 | 11103 | 0.9261 | 0.9442 |
MCF 10A | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 6112 | 11103 | 0.5505 | 0.6048 |
MCF 10A | XMD16-144 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 2195 | 11103 | 0.1977 | 0.1000 |
MCF 10A | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2092 | 11103 | 0.1885 | 0.0808 |
MCF 10A | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2238 | 11103 | 0.2015 | 0.1080 |
MCF 10A | XMD16-144 | 10 | uM | LJP5 | 72 | hr | 1694 | 1290 | 11103 | 0.1162 | -0.0957 |
MCF 10A | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 1694 | 10798 | 11103 | 0.9725 | 0.9795 |
MCF 10A | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 9664 | 11103 | 0.8704 | 0.9002 |
MCF 10A | Erlotinib | 0.37 | uM | LJP5 | 72 | hr | 1694 | 6099 | 11103 | 0.5493 | 0.6036 |
MCF 10A | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2452 | 11103 | 0.2209 | 0.1456 |
MCF 10A | Erlotinib | 3.33 | uM | LJP5 | 72 | hr | 1694 | 2713 | 11103 | 0.2444 | 0.1893 |
MCF 10A | Erlotinib | 10 | uM | LJP5 | 72 | hr | 1694 | 2603 | 11103 | 0.2345 | 0.1712 |
MCF 10A | Gefitinib | 0.04 | uM | LJP6 | 72 | hr | 1694 | 10005 | 11217 | 0.8920 | 0.9177 |
MCF 10A | Gefitinib | 0.12 | uM | LJP6 | 72 | hr | 1694 | 6990 | 11217 | 0.6231 | 0.6811 |
MCF 10A | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 3801 | 11217 | 0.3389 | 0.3442 |
MCF 10A | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2260 | 11217 | 0.2014 | 0.1111 |
MCF 10A | Gefitinib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 2475 | 11217 | 0.2206 | 0.1484 |
MCF 10A | Gefitinib | 10 | uM | LJP6 | 72 | hr | 1694 | 2309 | 11217 | 0.2059 | 0.1203 |
MCF 10A | Nilotinib | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11366 | 11103 | 1.0237 | 1.0173 |
MCF 10A | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11259 | 11103 | 1.0140 | 1.0102 |
MCF 10A | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1694 | 11157 | 11103 | 1.0049 | 1.0036 |