LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A XMD11-85h
0.37
uM
LJP6
72
hr
1694 11087 11217 0.9884 0.9915
MCF 10A XMD11-85h
1.11
uM
LJP6
72
hr
1694 10893 11217 0.9711 0.9785
MCF 10A XMD11-85h
3.33
uM
LJP6
72
hr
1694 10639 11217 0.9486 0.9616
MCF 10A XMD11-85h
10
uM
LJP6
72
hr
1694 9171 11217 0.8177 0.8576
MCF 10A XMD16-144
0.04
uM
LJP5
72
hr
1694 10283 11103 0.9261 0.9442
MCF 10A XMD16-144
0.12
uM
LJP5
72
hr
1694 6112 11103 0.5505 0.6048
MCF 10A XMD16-144
0.37
uM
LJP5
72
hr
1694 2195 11103 0.1977 0.1000
MCF 10A XMD16-144
1.11
uM
LJP5
72
hr
1694 2092 11103 0.1885 0.0808
MCF 10A XMD16-144
3.33
uM
LJP5
72
hr
1694 2238 11103 0.2015 0.1080
MCF 10A XMD16-144
10
uM
LJP5
72
hr
1694 1290 11103 0.1162 -0.0957
MCF 10A Erlotinib
0.04
uM
LJP5
72
hr
1694 10798 11103 0.9725 0.9795
MCF 10A Erlotinib
0.12
uM
LJP5
72
hr
1694 9664 11103 0.8704 0.9002
MCF 10A Erlotinib
0.37
uM
LJP5
72
hr
1694 6099 11103 0.5493 0.6036
MCF 10A Erlotinib
1.11
uM
LJP5
72
hr
1694 2452 11103 0.2209 0.1456
MCF 10A Erlotinib
3.33
uM
LJP5
72
hr
1694 2713 11103 0.2444 0.1893
MCF 10A Erlotinib
10
uM
LJP5
72
hr
1694 2603 11103 0.2345 0.1712
MCF 10A Gefitinib
0.04
uM
LJP6
72
hr
1694 10005 11217 0.8920 0.9177
MCF 10A Gefitinib
0.12
uM
LJP6
72
hr
1694 6990 11217 0.6231 0.6811
MCF 10A Gefitinib
0.37
uM
LJP6
72
hr
1694 3801 11217 0.3389 0.3442
MCF 10A Gefitinib
1.11
uM
LJP6
72
hr
1694 2260 11217 0.2014 0.1111
MCF 10A Gefitinib
3.33
uM
LJP6
72
hr
1694 2475 11217 0.2206 0.1484
MCF 10A Gefitinib
10
uM
LJP6
72
hr
1694 2309 11217 0.2059 0.1203
MCF 10A Nilotinib
0.04
uM
LJP5
72
hr
1694 11366 11103 1.0237 1.0173
MCF 10A Nilotinib
0.12
uM
LJP5
72
hr
1694 11259 11103 1.0140 1.0102
MCF 10A Nilotinib
0.37
uM
LJP5
72
hr
1694 11157 11103 1.0049 1.0036