LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GSK1059615
0.04
uM
LJP5
 72
hr
 1694 11327 11103 1.0201 1.0147
MCF 10A GSK1059615
0.04
uM
LJP6
 72
hr
 1694 11024 11217 0.9829 0.9873
MCF 10A GSK1059615
0.12
uM
LJP5
 72
hr
 1694 10702 11103 0.9639 0.9731
MCF 10A GSK1059615
0.12
uM
LJP6
 72
hr
 1694 9624 11217 0.8580 0.8908
MCF 10A GSK1059615
0.37
uM
LJP5
 72
hr
 1694 7368 11103 0.6637 0.7194
MCF 10A GSK1059615
0.37
uM
LJP6
 72
hr
 1694 6672 11217 0.5949 0.6530
MCF 10A GSK1059615
1.11
uM
LJP5
 72
hr
 1694 2596 11103 0.2339 0.1700
MCF 10A GSK1059615
1.11
uM
LJP6
 72
hr
 1694 3081 11217 0.2745 0.2424
MCF 10A GSK1059615
3.33
uM
LJP5
 72
hr
 1694 1343 11103 0.1209 -0.0842
MCF 10A GSK1059615
3.33
uM
LJP6
 72
hr
 1694 2032 11217 0.1810 0.0663
MCF 10A GSK1059615
10
uM
LJP5
 72
hr
 1694 1469 11103 0.1323 -0.0513
MCF 10A GSK1059615
10
uM
LJP6
 72
hr
 1694 1500 11217 0.1337 -0.0462
MCF 10A Brivanib
0.04
uM
LJP5
 72
hr
 1694 11133 11103 1.0027 1.0020
MCF 10A Brivanib
0.12
uM
LJP5
 72
hr
 1694 10774 11103 0.9704 0.9779
MCF 10A Brivanib
0.37
uM
LJP5
 72
hr
 1694 10776 11103 0.9705 0.9781
MCF 10A Brivanib
1.11
uM
LJP5
 72
hr
 1694 9380 11103 0.8449 0.8794
MCF 10A Brivanib
3.33
uM
LJP5
 72
hr
 1694 7914 11103 0.7127 0.7651
MCF 10A Brivanib
10
uM
LJP5
 72
hr
 1694 3918 11103 0.3529 0.3619
MCF 10A CHIR-99021
0.04
uM
LJP6
 72
hr
 1694 11560 11217 1.0305 1.0221
MCF 10A CHIR-99021
0.12
uM
LJP6
 72
hr
 1694 11662 11217 1.0398 1.0288
MCF 10A CHIR-99021
0.37
uM
LJP6
 72
hr
 1694 11724 11217 1.0453 1.0327
MCF 10A CHIR-99021
1.11
uM
LJP6
 72
hr
 1694 11631 11217 1.0372 1.0267
MCF 10A CHIR-99021
3.33
uM
LJP6
 72
hr
 1694 10634 11217 0.9480 0.9610
MCF 10A CHIR-99021
10
uM
LJP6
 72
hr
 1694 9109 11217 0.8119 0.8519
MCF 10A Linifanib
0.04
uM
LJP6
 72
hr
 1694 11701 11217 1.0431 1.0312