LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Canertinib
0.04
uM
LJP6
 72
hr
 1694 9108 11217 0.8121 0.8530
MCF 10A Canertinib
0.12
uM
LJP6
 72
hr
 1694 6493 11217 0.5791 0.6362
MCF 10A Canertinib
0.37
uM
LJP6
 72
hr
 1694 4255 11217 0.3795 0.4012
MCF 10A Canertinib
1.11
uM
LJP6
 72
hr
 1694 2738 11217 0.2443 0.1916
MCF 10A Canertinib
3.33
uM
LJP6
 72
hr
 1694 2228 11217 0.1987 0.1055
MCF 10A Canertinib
10
uM
LJP6
 72
hr
 1694 115 11217 0.0103 -0.6274
MCF 10A NVP-AEW541
0.04
uM
LJP5
 72
hr
 1694 10983 11103 0.9892 0.9920
MCF 10A NVP-AEW541
0.12
uM
LJP5
 72
hr
 1694 10777 11103 0.9706 0.9781
MCF 10A NVP-AEW541
0.37
uM
LJP5
 72
hr
 1694 10089 11103 0.9086 0.9305
MCF 10A NVP-AEW541
1.11
uM
LJP5
 72
hr
 1694 8455 11103 0.7614 0.8086
MCF 10A NVP-AEW541
3.33
uM
LJP5
 72
hr
 1694 8576 11103 0.7724 0.8183
MCF 10A NVP-AEW541
10
uM
LJP5
 72
hr
 1694 5107 11103 0.4600 0.5019
MCF 10A PHA-665752
0.04
uM
LJP5
 72
hr
 1694 11057 11103 0.9958 0.9969
MCF 10A PHA-665752
0.12
uM
LJP5
 72
hr
 1694 10792 11103 0.9720 0.9791
MCF 10A PHA-665752
0.37
uM
LJP5
 72
hr
 1694 10794 11103 0.9721 0.9792
MCF 10A PHA-665752
1.11
uM
LJP5
 72
hr
 1694 10464 11103 0.9424 0.9567
MCF 10A PHA-665752
3.33
uM
LJP5
 72
hr
 1694 10469 11103 0.9428 0.9570
MCF 10A PHA-665752
10
uM
LJP5
 72
hr
 1694 9302 11103 0.8378 0.8737
MCF 10A PI103
0.04
uM
LJP6
 72
hr
 1694 11606 11217 1.0346 1.0249
MCF 10A PI103
0.12
uM
LJP6
 72
hr
 1694 11398 11217 1.0162 1.0118
MCF 10A PI103
0.37
uM
LJP6
 72
hr
 1694 7232 11217 0.6445 0.7015
MCF 10A PI103
1.11
uM
LJP6
 72
hr
 1694 3253 11217 0.2899 0.2694
MCF 10A PI103
3.33
uM
LJP6
 72
hr
 1694 2550 11217 0.2273 0.1617
MCF 10A PI103
10
uM
LJP6
 72
hr
 1694 2227 11217 0.1985 0.1048
MCF 10A Dovitinib
0.04
uM
LJP5
 72
hr
 1694 10366 11103 0.9336 0.9500