LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10835 | 10362 | 1.0457 | 1.0206 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10826 | 10473 | 1.0337 | 1.0152 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10774 | 10362 | 1.0399 | 1.0179 |
| MCF 10A | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10725 | 10362 | 1.0350 | 1.0159 |
| MCF 10A | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 513 | 10721 | 10362 | 1.0349 | 1.0157 |
| MCF 10A | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10715 | 10362 | 1.0340 | 1.0153 |
| MCF 10A | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 513 | 10714 | 10473 | 1.0230 | 1.0105 |
| MCF 10A | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10711 | 10362 | 1.0337 | 1.0153 |
| MCF 10A | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10700 | 10362 | 1.0328 | 1.0148 |
| MCF 10A | XL147 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10693 | 10362 | 1.0321 | 1.0145 |
| MCF 10A | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 513 | 10692 | 10473 | 1.0210 | 1.0095 |
| MCF 10A | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10673 | 10362 | 1.0305 | 1.0133 |
| MCF 10A | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10627 | 10362 | 1.0254 | 1.0115 |
| MCF 10A | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10621 | 10362 | 1.0251 | 1.0113 |
| MCF 10A | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 10609 | 10362 | 1.0239 | 1.0109 |
| MCF 10A | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10600 | 10362 | 1.0224 | 1.0094 |
| MCF 10A | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 513 | 10587 | 10473 | 1.0108 | 1.0047 |
| MCF 10A | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 513 | 10571 | 10473 | 1.0094 | 1.0043 |
| MCF 10A | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 513 | 10543 | 10473 | 1.0068 | 1.0030 |
| MCF 10A | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 513 | 10535 | 10473 | 1.0061 | 1.0025 |
| MCF 10A | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 513 | 10522 | 10473 | 1.0047 | 1.0020 |
| MCF 10A | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 513 | 10502 | 10473 | 1.0029 | 1.0010 |
| MCF 10A | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 513 | 10484 | 10473 | 1.0012 | 1.0005 |
| MCF 10A | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10462 | 10362 | 1.0098 | 1.0045 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10459 | 10473 | 0.9986 | 0.9993 |