LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 GW843682X
0.37
uM
LJP6
 72
hr
 1235 1517 4056 0.3744 0.1272
MCF7 GW843682X
1.11
uM
LJP6
 72
hr
 1235 1433 4056 0.3534 0.0904
MCF7 GW843682X
3.33
uM
LJP6
 72
hr
 1235 1328 4056 0.3277 0.0433
MCF7 GW843682X
10
uM
LJP6
 72
hr
 1235 1612 4056 0.3976 0.1682
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1235 3513 4267 0.8246 0.7956
MCF7 HG-5-113-01
0.12
uM
LJP5
 72
hr
 1235 2603 4267 0.6116 0.5180
MCF7 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1235 1706 4267 0.4006 0.1983
MCF7 HG-5-113-01
1.11
uM
LJP5
 72
hr
 1235 1446 4267 0.3389 0.0915
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1235 1371 4267 0.3216 0.0600
MCF7 HG-5-113-01
10
uM
LJP5
 72
hr
 1235 883 4267 0.2073 -0.1712
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1235 2625 4056 0.6466 0.5496
MCF7 HG-5-88-01
0.12
uM
LJP6
 72
hr
 1235 2639 4056 0.6514 0.5573
MCF7 HG-5-88-01
0.37
uM
LJP6
 72
hr
 1235 2225 4056 0.5484 0.4088
MCF7 HG-5-88-01
1.11
uM
LJP6
 72
hr
 1235 1895 4056 0.4673 0.2834
MCF7 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1235 1501 4056 0.3699 0.1198
MCF7 HG-5-88-01
10
uM
LJP6
 72
hr
 1235 1192 4056 0.2939 -0.0207
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1235 4834 4056 1.1918 1.2152
MCF7 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1235 4613 4056 1.1372 1.1557
MCF7 HG-6-64-01
0.37
uM
LJP6
 72
hr
 1235 3989 4056 0.9847 0.9816
MCF7 HG-6-64-01
1.11
uM
LJP6
 72
hr
 1235 3432 4056 0.8470 0.8153
MCF7 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1235 2586 4056 0.6377 0.5385
MCF7 HG-6-64-01
10
uM
LJP6
 72
hr
 1235 701 4056 0.1733 -0.2817
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1235 3207 4267 0.7514 0.7040
MCF7 Neratinib
0.12
uM
LJP5
 72
hr
 1235 2830 4267 0.6631 0.5890
MCF7 Neratinib
0.37
uM
LJP5
 72
hr
 1235 2689 4267 0.6306 0.5451