LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3561 | 4056 | 0.8777 | 0.8530 |
| MCF7 | Sorafenib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 3908 | 4056 | 0.9638 | 0.9574 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3680 | 4056 | 0.9076 | 0.8897 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 3446 | 4056 | 0.8503 | 0.8195 |
| MCF7 | Sorafenib | 10 | uM | LJP6 | 72 | hr | 1235 | 1645 | 4056 | 0.4061 | 0.1821 |
| MCF7 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4851 | 4267 | 1.1371 | 1.1490 |
| MCF7 | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4537 | 4267 | 1.0633 | 1.0695 |
| MCF7 | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4829 | 4267 | 1.1306 | 1.1406 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4687 | 4267 | 1.0985 | 1.1079 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4230 | 4267 | 0.9910 | 0.9888 |
| MCF7 | CP466722 | 10 | uM | LJP5 | 72 | hr | 1235 | 1972 | 4267 | 0.4623 | 0.2987 |
| MCF7 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3247 | 4267 | 0.7619 | 0.7178 |
| MCF7 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3363 | 4267 | 0.7888 | 0.7515 |
| MCF7 | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 3410 | 4267 | 0.7997 | 0.7651 |
| MCF7 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3304 | 4267 | 0.7743 | 0.7334 |
| MCF7 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3278 | 4267 | 0.7684 | 0.7259 |
| MCF7 | CP724714 | 10 | uM | LJP5 | 72 | hr | 1235 | 2110 | 4267 | 0.4950 | 0.3495 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1126 | 4056 | 0.2776 | -0.0528 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 676 | 4056 | 0.1668 | -0.2966 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 694 | 4056 | 0.1712 | -0.2854 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 573 | 4056 | 0.1413 | -0.3613 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 542 | 4056 | 0.1338 | -0.3813 |
| MCF7 | Alvocidib | 10 | uM | LJP6 | 72 | hr | 1235 | 512 | 4056 | 0.1258 | -0.4073 |
| MCF7 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3022 | 4056 | 0.7449 | 0.6839 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1616 | 4056 | 0.3977 | 0.1658 |