LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PHA-793887 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1311 | 4056 | 0.3231 | 0.0348 |
| MCF7 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1381 | 4056 | 0.3403 | 0.0663 |
| MCF7 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1216 | 4056 | 0.2996 | -0.0104 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1207 | 4056 | 0.2975 | -0.0139 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1143 | 4056 | 0.2814 | -0.0461 |
| MCF7 | PHA-793887 | 10 | uM | LJP6 | 72 | hr | 1235 | 639 | 4056 | 0.1575 | -0.3203 |
| MCF7 | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1814 | 4056 | 0.4463 | 0.2452 |
| MCF7 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1647 | 4056 | 0.4057 | 0.1814 |
| MCF7 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1715 | 4056 | 0.4231 | 0.2106 |
| MCF7 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1553 | 4056 | 0.3832 | 0.1422 |
| MCF7 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1527 | 4056 | 0.3764 | 0.1310 |
| MCF7 | QL-X-138 | 10 | uM | LJP6 | 72 | hr | 1235 | 1078 | 4056 | 0.2660 | -0.0760 |
| MCF7 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2788 | 4056 | 0.6870 | 0.6061 |
| MCF7 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1806 | 4056 | 0.4443 | 0.2434 |
| MCF7 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1131 | 4056 | 0.2790 | -0.0499 |
| MCF7 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 951 | 4056 | 0.2347 | -0.1412 |
| MCF7 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 979 | 4056 | 0.2413 | -0.1272 |
| MCF7 | QL-XII-47 | 10 | uM | LJP6 | 72 | hr | 1235 | 1019 | 4056 | 0.2512 | -0.1081 |
| MCF7 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1714 | 4056 | 0.4227 | 0.2106 |
| MCF7 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1509 | 4056 | 0.3724 | 0.1232 |
| MCF7 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1398 | 4056 | 0.3448 | 0.0747 |
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1185 | 4056 | 0.2923 | -0.0238 |
| MCF7 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1097 | 4056 | 0.2706 | -0.0670 |
| MCF7 | Torin1 | 10 | uM | LJP6 | 72 | hr | 1235 | 1138 | 4056 | 0.2804 | -0.0477 |
| MCF7 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1225 | 4267 | 0.2870 | -0.0052 |