LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 XL147
3.33
uM
LJP5
 72
hr
 1235 4700 4267 1.1015 1.1105
MCF7 XL147
10
uM
LJP5
 72
hr
 1235 2690 4267 0.6313 0.5461
MCF7 Y39983
0.04
uM
LJP6
 72
hr
 1235 4249 4056 1.0481 1.0557
MCF7 Y39983
0.12
uM
LJP6
 72
hr
 1235 4182 4056 1.0309 1.0357
MCF7 Y39983
0.37
uM
LJP6
 72
hr
 1235 4011 4056 0.9891 0.9875
MCF7 Y39983
1.11
uM
LJP6
 72
hr
 1235 3338 4056 0.8233 0.7859
MCF7 Y39983
3.33
uM
LJP6
 72
hr
 1235 2251 4056 0.5550 0.4189
MCF7 Y39983
10
uM
LJP6
 72
hr
 1235 622 4056 0.1532 -0.3307
MCF7 Nintedanib
0.04
uM
LJP6
 72
hr
 1235 3999 4056 0.9865 0.9829
MCF7 Nintedanib
0.12
uM
LJP6
 72
hr
 1235 3521 4056 0.8674 0.8398
MCF7 Nintedanib
0.37
uM
LJP6
 72
hr
 1235 2792 4056 0.6888 0.6088
MCF7 Nintedanib
1.11
uM
LJP6
 72
hr
 1235 2119 4056 0.5228 0.3700
MCF7 Nintedanib
3.33
uM
LJP6
 72
hr
 1235 1463 4056 0.3603 0.1021
MCF7 Nintedanib
10
uM
LJP6
 72
hr
 1235 844 4056 0.2079 -0.2001
MCF7 Foretinib
0.04
uM
LJP5
 72
hr
 1235 4219 4267 0.9882 0.9860
MCF7 Foretinib
0.12
uM
LJP5
 72
hr
 1235 1873 4267 0.4387 0.2612
MCF7 Foretinib
0.37
uM
LJP5
 72
hr
 1235 1523 4267 0.3568 0.1231
MCF7 Foretinib
1.11
uM
LJP5
 72
hr
 1235 1412 4267 0.3308 0.0768
MCF7 Foretinib
3.33
uM
LJP5
 72
hr
 1235 1290 4267 0.3020 0.0228
MCF7 Foretinib
10
uM
LJP5
 72
hr
 1235 839 4267 0.1964 -0.1961
MCF7 AZD 5438
0.04
uM
LJP6
 72
hr
 1235 3569 4056 0.8797 0.8554
MCF7 AZD 5438
0.12
uM
LJP6
 72
hr
 1235 2135 4056 0.5263 0.3756
MCF7 AZD 5438
0.37
uM
LJP6
 72
hr
 1235 1345 4056 0.3321 0.0508
MCF7 AZD 5438
1.11
uM
LJP6
 72
hr
 1235 1192 4056 0.2939 -0.0207
MCF7 AZD 5438
3.33
uM
LJP6
 72
hr
 1235 779 4056 0.1922 -0.2358