LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 1235 1543 4578 0.3370 0.1246
MDA-MB-231 Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 1235 1355 4929 0.2749 0.0472
MDA-MB-231 Barasertib
10
uM
LJP5
 1
D07
 72
hr
 1235 1355 4474 0.3028 0.0508
MDA-MB-231 Barasertib
10
uM
LJP5
 2
D07
 72
hr
 1235 1446 4578 0.3158 0.0866
MDA-MB-231 Barasertib
10
uM
LJP5
 3
D07
 72
hr
 1235 1392 4929 0.2824 0.0614
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 1235 4859 4474 1.0859 1.0908
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 1235 4836 4578 1.0562 1.0588
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 1235 4541 4929 0.9212 0.9195
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 1235 4583 4474 1.0242 1.0259
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 1235 4685 4578 1.0232 1.0245
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 1235 4678 4929 0.9490 0.9483
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 1235 4637 4474 1.0363 1.0388
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 1235 4692 4578 1.0248 1.0261
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 1235 4513 4929 0.9156 0.9135
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 1235 4166 4474 0.9310 0.9244
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 1235 4627 4578 1.0106 1.0112
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 1235 4320 4929 0.8764 0.8721
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 1235 4115 4474 0.9196 0.9117
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 1235 4115 4578 0.8988 0.8901
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 1235 4444 4929 0.9016 0.8988
MDA-MB-231 Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 1235 2106 4474 0.4706 0.3326
MDA-MB-231 Vemurafenib
10
uM
LJP5
 2
C13
 72
hr
 1235 2395 4578 0.5231 0.4193
MDA-MB-231 Vemurafenib
10
uM
LJP5
 3
C13
 72
hr
 1235 2339 4929 0.4745 0.3766
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 1
D18
 72
hr
 1235 4495 4474 1.0045 1.0049
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 2
D18
 72
hr
 1235 4868 4578 1.0632 1.0660