LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 3
D18
 72
hr
 1235 4692 4929 0.9519 0.9512
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 1
D17
 72
hr
 1235 4911 4474 1.0975 1.1028
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 2
D17
 72
hr
 1235 4653 4578 1.0163 1.0171
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 3
D17
 72
hr
 1235 5071 4929 1.0287 1.0286
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 1235 4682 4474 1.0463 1.0494
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 1235 5020 4578 1.0964 1.0998
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 1235 4785 4929 0.9707 0.9705
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 1
D15
 72
hr
 1235 4859 4474 1.0859 1.0908
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 2
D15
 72
hr
 1235 4923 4578 1.0752 1.0783
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 3
D15
 72
hr
 1235 4869 4929 0.9878 0.9877
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 1235 4625 4474 1.0336 1.0359
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 1235 4850 4578 1.0593 1.0619
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 1235 4952 4929 1.0046 1.0046
MDA-MB-231 Enzastaurin
10
uM
LJP5
 1
D13
 72
hr
 1235 4842 4474 1.0821 1.0868
MDA-MB-231 Enzastaurin
10
uM
LJP5
 2
D13
 72
hr
 1235 5273 4578 1.1517 1.1552
MDA-MB-231 Enzastaurin
10
uM
LJP5
 3
D13
 72
hr
 1235 5417 4929 1.0989 1.0968
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 1235 2774 4355 0.6368 0.5603
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 1235 2740 4277 0.6406 0.5597
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 1235 2998 4583 0.6541 0.5978
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 1235 2435 4355 0.5590 0.4523
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 1235 2555 4277 0.5973 0.5000
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 1235 2722 4583 0.5939 0.5183
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 1235 2114 4355 0.4853 0.3436
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 1235 2371 4277 0.5543 0.4387
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 1235 2333 4583 0.5090 0.3994