LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PD184352
0.12
uM
LJP5
 2
L11
 72
hr
 1235 3966 4578 0.8662 0.8536
MDA-MB-231 PD184352
0.12
uM
LJP5
 3
L11
 72
hr
 1235 4396 4929 0.8918 0.8885
MDA-MB-231 PD184352
0.37
uM
LJP5
 1
L10
 72
hr
 1235 3481 4474 0.7779 0.7469
MDA-MB-231 PD184352
0.37
uM
LJP5
 2
L10
 72
hr
 1235 3777 4578 0.8249 0.8063
MDA-MB-231 PD184352
0.37
uM
LJP5
 3
L10
 72
hr
 1235 4076 4929 0.8269 0.8183
MDA-MB-231 PD184352
1.11
uM
LJP5
 1
L09
 72
hr
 1235 3139 4474 0.7015 0.6523
MDA-MB-231 PD184352
1.11
uM
LJP5
 2
L09
 72
hr
 1235 3302 4578 0.7212 0.6823
MDA-MB-231 PD184352
1.11
uM
LJP5
 3
L09
 72
hr
 1235 3688 4929 0.7482 0.7294
MDA-MB-231 PD184352
3.33
uM
LJP5
 1
L08
 72
hr
 1235 2548 4474 0.5694 0.4766
MDA-MB-231 PD184352
3.33
uM
LJP5
 2
L08
 72
hr
 1235 3063 4578 0.6690 0.6167
MDA-MB-231 PD184352
3.33
uM
LJP5
 3
L08
 72
hr
 1235 3201 4929 0.6494 0.6110
MDA-MB-231 PD184352
10
uM
LJP5
 1
L07
 72
hr
 1235 1314 4474 0.2937 0.0335
MDA-MB-231 PD184352
10
uM
LJP5
 2
L07
 72
hr
 1235 1434 4578 0.3132 0.0818
MDA-MB-231 PD184352
10
uM
LJP5
 3
L07
 72
hr
 1235 1600 4929 0.3246 0.1381
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 1
K06
 72
hr
 1235 4023 4474 0.8991 0.8886
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 2
K06
 72
hr
 1235 4049 4578 0.8843 0.8740
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 3
K06
 72
hr
 1235 4914 4929 0.9969 0.9969
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 1
K05
 72
hr
 1235 4190 4474 0.9364 0.9304
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 2
K05
 72
hr
 1235 4268 4578 0.9322 0.9270
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 3
K05
 72
hr
 1235 4911 4929 0.9963 0.9963
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 1
K04
 72
hr
 1235 4119 4474 0.9205 0.9127
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 2
K04
 72
hr
 1235 4260 4578 0.9304 0.9251
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 3
K04
 72
hr
 1235 5234 4929 1.0618 1.0610
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 1
K03
 72
hr
 1235 4117 4474 0.9201 0.9122
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 1235 4261 4578 0.9306 0.9253