LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 3
K03
 72
hr
 1235 4834 4929 0.9807 0.9805
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 1
K02
 72
hr
 1235 3813 4474 0.8521 0.8348
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 1235 3704 4578 0.8090 0.7877
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 1235 4675 4929 0.9484 0.9476
MDA-MB-231 PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 1235 3784 4474 0.8456 0.8273
MDA-MB-231 PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 1235 3361 4578 0.7341 0.6981
MDA-MB-231 PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 1235 4352 4929 0.8829 0.8790
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 1235 3958 4355 0.9087 0.8973
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 1235 3738 4277 0.8739 0.8550
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 1235 4198 4583 0.9159 0.9092
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 1235 4024 4355 0.9238 0.9147
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 1235 4051 4277 0.9471 0.9402
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 1235 4331 4583 0.9449 0.9410
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 1235 4142 4355 0.9509 0.9453
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 1235 4177 4277 0.9765 0.9737
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 1235 4442 4583 0.9692 0.9671
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 1235 4010 4355 0.9206 0.9110
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 1235 4072 4277 0.9520 0.9458
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 1235 4289 4583 0.9358 0.9310
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 1235 4277 4355 0.9819 0.9800
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 1235 4180 4277 0.9772 0.9745
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 1235 4247 4583 0.9266 0.9210
MDA-MB-231 Lapatinib
10
uM
LJP6
 1
M19
 72
hr
 1235 2608 4355 0.5987 0.5082
MDA-MB-231 Lapatinib
10
uM
LJP6
 2
M19
 72
hr
 1235 2675 4277 0.6254 0.5389
MDA-MB-231 Lapatinib
10
uM
LJP6
 3
M19
 72
hr
 1235 2524 4583 0.5507 0.4588