LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 1235 3600 4355 0.8265 0.8009
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 1235 3301 4277 0.7717 0.7306
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 1235 3482 4583 0.7597 0.7294
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 1235 3573 4355 0.8203 0.7934
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 1235 3482 4277 0.8141 0.7830
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 1235 3400 4583 0.7418 0.7078
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 1235 3589 4355 0.8239 0.7978
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 1235 3369 4277 0.7876 0.7504
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 1235 3461 4583 0.7551 0.7239
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 1235 3633 4355 0.8340 0.8099
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 1235 3543 4277 0.8283 0.8004
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 1235 3431 4583 0.7486 0.7160
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 1
L14
 72
hr
 1235 3306 4355 0.7590 0.7184
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 2
L14
 72
hr
 1235 3177 4277 0.7428 0.6940
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 3
L14
 72
hr
 1235 3451 4583 0.7529 0.7213
MDA-MB-231 Sirolimus
10
uM
LJP6
 1
L13
 72
hr
 1235 3357 4355 0.7707 0.7329
MDA-MB-231 Sirolimus
10
uM
LJP6
 2
L13
 72
hr
 1235 3042 4277 0.7112 0.6535
MDA-MB-231 Sirolimus
10
uM
LJP6
 3
L13
 72
hr
 1235 3424 4583 0.7471 0.7141
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 1235 3601 4355 0.8267 0.8011
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 1235 3732 4277 0.8725 0.8534
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 1235 3709 4583 0.8092 0.7882
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 1
M17
 72
hr
 1235 3509 4355 0.8056 0.7757
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 2
M17
 72
hr
 1235 3492 4277 0.8164 0.7858
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 3
M17
 72
hr
 1235 3566 4583 0.7780 0.7514
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 1
M16
 72
hr
 1235 3394 4355 0.7792 0.7434