LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 2
M16
 72
hr
 1235 3337 4277 0.7802 0.7411
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 3
M16
 72
hr
 1235 3170 4583 0.6916 0.6457
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 1
M15
 72
hr
 1235 2859 4355 0.6564 0.5864
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 2
M15
 72
hr
 1235 2928 4277 0.6845 0.6186
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 3
M15
 72
hr
 1235 2753 4583 0.6007 0.5274
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 1
M14
 72
hr
 1235 2224 4355 0.5106 0.3816
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 2
M14
 72
hr
 1235 2502 4277 0.5849 0.4825
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 3
M14
 72
hr
 1235 2397 4583 0.5230 0.4195
MDA-MB-231 ZSTK474
10
uM
LJP6
 1
M13
 72
hr
 1235 1607 4355 0.3689 0.1554
MDA-MB-231 ZSTK474
10
uM
LJP6
 2
M13
 72
hr
 1235 1981 4277 0.4631 0.3013
MDA-MB-231 ZSTK474
10
uM
LJP6
 3
M13
 72
hr
 1235 2117 4583 0.4619 0.3293
MDA-MB-231 BX-912
0.04
uM
LJP5
 1
L24
 72
hr
 1235 3992 4474 0.8921 0.8807
MDA-MB-231 BX-912
0.04
uM
LJP5
 2
L24
 72
hr
 1235 4021 4578 0.8782 0.8672
MDA-MB-231 BX-912
0.04
uM
LJP5
 3
L24
 72
hr
 1235 4880 4929 0.9900 0.9900
MDA-MB-231 BX-912
0.12
uM
LJP5
 1
L23
 72
hr
 1235 3485 4474 0.7788 0.7480
MDA-MB-231 BX-912
0.12
uM
LJP5
 2
L23
 72
hr
 1235 3989 4578 0.8712 0.8593
MDA-MB-231 BX-912
0.12
uM
LJP5
 3
L23
 72
hr
 1235 4076 4929 0.8269 0.8183
MDA-MB-231 BX-912
0.37
uM
LJP5
 1
L22
 72
hr
 1235 1895 4474 0.4235 0.2589
MDA-MB-231 BX-912
0.37
uM
LJP5
 2
L22
 72
hr
 1235 2230 4578 0.4871 0.3667
MDA-MB-231 BX-912
0.37
uM
LJP5
 3
L22
 72
hr
 1235 2272 4929 0.4609 0.3567
MDA-MB-231 BX-912
1.11
uM
LJP5
 1
L21
 72
hr
 1235 1458 4474 0.3258 0.0931
MDA-MB-231 BX-912
1.11
uM
LJP5
 2
L21
 72
hr
 1235 1575 4578 0.3440 0.1369
MDA-MB-231 BX-912
1.11
uM
LJP5
 3
L21
 72
hr
 1235 1809 4929 0.3670 0.2103
MDA-MB-231 BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 1235 1204 4474 0.2691 -0.0140
MDA-MB-231 BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 1235 1274 4578 0.2783 0.0162