LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 BMS345541
1.11
uM
LJP6
 1
D03
 72
hr
 1235 2707 4355 0.6215 0.5394
MDA-MB-231 BMS345541
1.11
uM
LJP6
 2
D03
 72
hr
 1235 2692 4277 0.6294 0.5444
MDA-MB-231 BMS345541
1.11
uM
LJP6
 3
D03
 72
hr
 1235 3147 4583 0.6866 0.6394
MDA-MB-231 BMS345541
3.33
uM
LJP6
 1
D02
 72
hr
 1235 1806 4355 0.4146 0.2321
MDA-MB-231 BMS345541
3.33
uM
LJP6
 2
D02
 72
hr
 1235 1714 4277 0.4007 0.2003
MDA-MB-231 BMS345541
3.33
uM
LJP6
 3
D02
 72
hr
 1235 1976 4583 0.4311 0.2817
MDA-MB-231 BMS345541
10
uM
LJP6
 1
D01
 72
hr
 1235 340 4355 0.0781 -0.5084
MDA-MB-231 BMS345541
10
uM
LJP6
 2
D01
 72
hr
 1235 418 4277 0.0977 -0.4541
MDA-MB-231 BMS345541
10
uM
LJP6
 3
D01
 72
hr
 1235 468 4583 0.1021 -0.4017
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 1
C12
 72
hr
 1235 3552 4355 0.8154 0.7876
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 2
C12
 72
hr
 1235 3624 4277 0.8473 0.8232
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 3
C12
 72
hr
 1235 4174 4583 0.9107 0.9035
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 1
C11
 72
hr
 1235 3160 4355 0.7255 0.6762
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 2
C11
 72
hr
 1235 3622 4277 0.8468 0.8227
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 3
C11
 72
hr
 1235 3650 4583 0.7964 0.7731
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 1
C10
 72
hr
 1235 3370 4355 0.7737 0.7366
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 2
C10
 72
hr
 1235 3697 4277 0.8643 0.8436
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 3
C10
 72
hr
 1235 3652 4583 0.7968 0.7736
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 1
C09
 72
hr
 1235 3464 4355 0.7952 0.7631
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 2
C09
 72
hr
 1235 3135 4277 0.7329 0.6815
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 3
C09
 72
hr
 1235 3383 4583 0.7381 0.7033
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 1
C08
 72
hr
 1235 3335 4355 0.7656 0.7267
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 2
C08
 72
hr
 1235 3146 4277 0.7355 0.6848
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 3
C08
 72
hr
 1235 3583 4583 0.7817 0.7558
MDA-MB-231 KIN001-043
10
uM
LJP6
 1
C07
 72
hr
 1235 1255 4355 0.2881 0.0085