LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 1235 1552 4929 0.3149 0.1209
MDA-MB-231 BX-912
10
uM
LJP5
 1
L19
 72
hr
 1235 559 4474 0.1249 -0.3478
MDA-MB-231 BX-912
10
uM
LJP5
 2
L19
 72
hr
 1235 638 4578 0.1393 -0.2953
MDA-MB-231 BX-912
10
uM
LJP5
 3
L19
 72
hr
 1235 793 4929 0.1609 -0.1994
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 1235 3726 4355 0.8554 0.8353
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 1235 3989 4277 0.9326 0.9236
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 1235 3949 4583 0.8616 0.8485
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 1235 3632 4355 0.8338 0.8097
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 1235 3681 4277 0.8606 0.8392
MDA-MB-231 Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 1235 3610 4583 0.7876 0.7628
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 1235 3133 4355 0.7193 0.6683
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 1235 2953 4277 0.6904 0.6263
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 1235 3172 4583 0.6921 0.6462
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 1235 2662 4355 0.6111 0.5253
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 1235 2885 4277 0.6745 0.6052
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 1235 2568 4583 0.5603 0.4722
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 1235 2269 4355 0.5209 0.3969
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 1235 2338 4277 0.5466 0.4275
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 1235 2389 4583 0.5212 0.4170
MDA-MB-231 Selumetinib
10
uM
LJP6
 1
M07
 72
hr
 1235 1652 4355 0.3793 0.1731
MDA-MB-231 Selumetinib
10
uM
LJP6
 2
M07
 72
hr
 1235 1483 4277 0.3467 0.1071
MDA-MB-231 Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 1235 1597 4583 0.3484 0.1452
MDA-MB-231 MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 1235 4148 4355 0.9523 0.9469
MDA-MB-231 MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 1235 3983 4277 0.9312 0.9220
MDA-MB-231 MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 1235 4169 4583 0.9096 0.9022