LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 1235 3919 4355 0.8997 0.8870
MDA-MB-231 MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 1235 3983 4277 0.9312 0.9220
MDA-MB-231 MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 1235 4093 4583 0.8930 0.8838
MDA-MB-231 MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 1235 3785 4355 0.8689 0.8512
MDA-MB-231 MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 1235 3773 4277 0.8821 0.8647
MDA-MB-231 MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 1235 4087 4583 0.8917 0.8824
MDA-MB-231 MK2206
1.11
uM
LJP6
 1
F03
 72
hr
 1235 3742 4355 0.8591 0.8396
MDA-MB-231 MK2206
1.11
uM
LJP6
 2
F03
 72
hr
 1235 3683 4277 0.8611 0.8397
MDA-MB-231 MK2206
1.11
uM
LJP6
 3
F03
 72
hr
 1235 3659 4583 0.7983 0.7754
MDA-MB-231 MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 1235 3264 4355 0.7493 0.7064
MDA-MB-231 MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 1235 3602 4277 0.8421 0.8170
MDA-MB-231 MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 1235 3498 4583 0.7632 0.7336
MDA-MB-231 MK2206
10
uM
LJP6
 1
F01
 72
hr
 1235 1437 4355 0.3299 0.0865
MDA-MB-231 MK2206
10
uM
LJP6
 2
F01
 72
hr
 1235 2188 4277 0.5115 0.3756
MDA-MB-231 MK2206
10
uM
LJP6
 3
F01
 72
hr
 1235 1943 4583 0.4239 0.2703
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 1
I06
 72
hr
 1235 4210 4474 0.9408 0.9354
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 2
I06
 72
hr
 1235 4197 4578 0.9167 0.9100
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 3
I06
 72
hr
 1235 4547 4929 0.9225 0.9207
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 1235 3781 4474 0.8450 0.8265
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 1235 4246 4578 0.9274 0.9217
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 1235 4368 4929 0.8861 0.8825
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 1
I04
 72
hr
 1235 3892 4474 0.8698 0.8552
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 2
I04
 72
hr
 1235 3911 4578 0.8542 0.8399
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 3
I04
 72
hr
 1235 4121 4929 0.8360 0.8283
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 1
I03
 72
hr
 1235 3574 4474 0.7987 0.7719