LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 2
I03
 72
hr
 1235 3714 4578 0.8112 0.7903
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 3
I03
 72
hr
 1235 4044 4929 0.8204 0.8111
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 1
I02
 72
hr
 1235 3359 4474 0.7507 0.7137
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 2
I02
 72
hr
 1235 3105 4578 0.6782 0.6284
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 3
I02
 72
hr
 1235 3679 4929 0.7464 0.7273
MDA-MB-231 AZD-6482
10
uM
LJP5
 1
I01
 72
hr
 1235 3033 4474 0.6778 0.6220
MDA-MB-231 AZD-6482
10
uM
LJP5
 2
I01
 72
hr
 1235 2898 4578 0.6330 0.5700
MDA-MB-231 AZD-6482
10
uM
LJP5
 3
I01
 72
hr
 1235 3259 4929 0.6612 0.6255
MDA-MB-231 NU7441
0.04
uM
LJP5
 1
C12
 72
hr
 1235 4865 4474 1.0872 1.0922
MDA-MB-231 NU7441
0.04
uM
LJP5
 2
C12
 72
hr
 1235 4699 4578 1.0263 1.0277
MDA-MB-231 NU7441
0.04
uM
LJP5
 3
C12
 72
hr
 1235 4889 4929 0.9918 0.9918
MDA-MB-231 NU7441
0.12
uM
LJP5
 1
C11
 72
hr
 1235 4865 4474 1.0872 1.0922
MDA-MB-231 NU7441
0.12
uM
LJP5
 2
C11
 72
hr
 1235 4802 4578 1.0488 1.0511
MDA-MB-231 NU7441
0.12
uM
LJP5
 3
C11
 72
hr
 1235 4227 4929 0.8575 0.8518
MDA-MB-231 NU7441
0.37
uM
LJP5
 1
C10
 72
hr
 1235 4594 4474 1.0267 1.0285
MDA-MB-231 NU7441
0.37
uM
LJP5
 2
C10
 72
hr
 1235 4510 4578 0.9850 0.9841
MDA-MB-231 NU7441
0.37
uM
LJP5
 3
C10
 72
hr
 1235 4572 4929 0.9275 0.9260
MDA-MB-231 NU7441
1.11
uM
LJP5
 1
C09
 72
hr
 1235 4205 4474 0.9397 0.9341
MDA-MB-231 NU7441
1.11
uM
LJP5
 2
C09
 72
hr
 1235 4254 4578 0.9291 0.9237
MDA-MB-231 NU7441
1.11
uM
LJP5
 3
C09
 72
hr
 1235 4179 4929 0.8478 0.8412
MDA-MB-231 NU7441
3.33
uM
LJP5
 1
C08
 72
hr
 1235 3115 4474 0.6961 0.6454
MDA-MB-231 NU7441
3.33
uM
LJP5
 2
C08
 72
hr
 1235 2593 4578 0.5663 0.4802
MDA-MB-231 NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 1235 2430 4929 0.4930 0.4032
MDA-MB-231 NU7441
10
uM
LJP5
 1
C07
 72
hr
 1235 1219 4474 0.2724 -0.0074
MDA-MB-231 NU7441
10
uM
LJP5
 2
C07
 72
hr
 1235 1209 4578 0.2641 -0.0116