LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 1
O08
 72
hr
 1235 866 4474 0.1935 -0.1744
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 2
O08
 72
hr
 1235 865 4578 0.1889 -0.1721
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 3
O08
 72
hr
 1235 911 4929 0.1848 -0.1417
MDA-MB-231 WH-4-025
10
uM
LJP5
 1
O07
 72
hr
 1235 425 4474 0.0950 -0.4374
MDA-MB-231 WH-4-025
10
uM
LJP5
 2
O07
 72
hr
 1235 460 4578 0.1005 -0.4074
MDA-MB-231 WH-4-025
10
uM
LJP5
 3
O07
 72
hr
 1235 377 4929 0.0765 -0.4484
MDA-MB-231 R406
0.04
uM
LJP6
 1
C18
 72
hr
 1235 4081 4355 0.9369 0.9295
MDA-MB-231 R406
0.04
uM
LJP6
 2
C18
 72
hr
 1235 4560 4277 1.0661 1.0727
MDA-MB-231 R406
0.04
uM
LJP6
 3
C18
 72
hr
 1235 4743 4583 1.0348 1.0365
MDA-MB-231 R406
0.12
uM
LJP6
 1
C17
 72
hr
 1235 4270 4355 0.9803 0.9782
MDA-MB-231 R406
0.12
uM
LJP6
 2
C17
 72
hr
 1235 4327 4277 1.0116 1.0129
MDA-MB-231 R406
0.12
uM
LJP6
 3
C17
 72
hr
 1235 4327 4583 0.9441 0.9400
MDA-MB-231 R406
0.37
uM
LJP6
 1
C16
 72
hr
 1235 3938 4355 0.9041 0.8920
MDA-MB-231 R406
0.37
uM
LJP6
 2
C16
 72
hr
 1235 4451 4277 1.0406 1.0449
MDA-MB-231 R406
0.37
uM
LJP6
 3
C16
 72
hr
 1235 4555 4583 0.9938 0.9935
MDA-MB-231 R406
1.11
uM
LJP6
 1
C15
 72
hr
 1235 3449 4355 0.7918 0.7589
MDA-MB-231 R406
1.11
uM
LJP6
 2
C15
 72
hr
 1235 4078 4277 0.9534 0.9474
MDA-MB-231 R406
1.11
uM
LJP6
 3
C15
 72
hr
 1235 4475 4583 0.9764 0.9749
MDA-MB-231 R406
3.33
uM
LJP6
 1
C14
 72
hr
 1235 2714 4355 0.6231 0.5416
MDA-MB-231 R406
3.33
uM
LJP6
 2
C14
 72
hr
 1235 3366 4277 0.7869 0.7496
MDA-MB-231 R406
3.33
uM
LJP6
 3
C14
 72
hr
 1235 3470 4583 0.7571 0.7263
MDA-MB-231 R406
10
uM
LJP6
 1
C13
 72
hr
 1235 1228 4355 0.2819 -0.0035
MDA-MB-231 R406
10
uM
LJP6
 2
C13
 72
hr
 1235 1475 4277 0.3448 0.1038
MDA-MB-231 R406
10
uM
LJP6
 3
C13
 72
hr
 1235 1242 4583 0.2710 0.0026
MDA-MB-231 BI-2536
0.04
uM
LJP6
 1
D18
 72
hr
 1235 911 4355 0.2091 -0.1545