LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 BI-2536
0.04
uM
LJP6
 2
D18
 72
hr
 1235 950 4277 0.2221 -0.1366
MDA-MB-231 BI-2536
0.04
uM
LJP6
 3
D18
 72
hr
 1235 1137 4583 0.2481 -0.0432
MDA-MB-231 BI-2536
0.12
uM
LJP6
 1
D17
 72
hr
 1235 1020 4355 0.2342 -0.1003
MDA-MB-231 BI-2536
0.12
uM
LJP6
 2
D17
 72
hr
 1235 1011 4277 0.2364 -0.1061
MDA-MB-231 BI-2536
0.12
uM
LJP6
 3
D17
 72
hr
 1235 1133 4583 0.2472 -0.0450
MDA-MB-231 BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 1235 917 4355 0.2105 -0.1515
MDA-MB-231 BI-2536
0.37
uM
LJP6
 2
D16
 72
hr
 1235 990 4277 0.2315 -0.1165
MDA-MB-231 BI-2536
0.37
uM
LJP6
 3
D16
 72
hr
 1235 1140 4583 0.2487 -0.0418
MDA-MB-231 BI-2536
1.11
uM
LJP6
 1
D15
 72
hr
 1235 953 4355 0.2188 -0.1333
MDA-MB-231 BI-2536
1.11
uM
LJP6
 2
D15
 72
hr
 1235 980 4277 0.2291 -0.1215
MDA-MB-231 BI-2536
1.11
uM
LJP6
 3
D15
 72
hr
 1235 1173 4583 0.2559 -0.0273
MDA-MB-231 BI-2536
3.33
uM
LJP6
 1
D14
 72
hr
 1235 954 4355 0.2190 -0.1328
MDA-MB-231 BI-2536
3.33
uM
LJP6
 2
D14
 72
hr
 1235 1053 4277 0.2462 -0.0856
MDA-MB-231 BI-2536
3.33
uM
LJP6
 3
D14
 72
hr
 1235 1267 4583 0.2764 0.0132
MDA-MB-231 BI-2536
10
uM
LJP6
 1
D13
 72
hr
 1235 611 4355 0.1403 -0.3214
MDA-MB-231 BI-2536
10
uM
LJP6
 2
D13
 72
hr
 1235 528 4277 0.1234 -0.3780
MDA-MB-231 BI-2536
10
uM
LJP6
 3
D13
 72
hr
 1235 714 4583 0.1558 -0.2519
MDA-MB-231 A443654
0.04
uM
LJP6
 1
I24
 72
hr
 1235 3533 4355 0.8111 0.7824
MDA-MB-231 A443654
0.04
uM
LJP6
 2
I24
 72
hr
 1235 3623 4277 0.8470 0.8229
MDA-MB-231 A443654
0.04
uM
LJP6
 3
I24
 72
hr
 1235 3431 4583 0.7486 0.7160
MDA-MB-231 A443654
0.12
uM
LJP6
 1
I23
 72
hr
 1235 2011 4355 0.4617 0.3072
MDA-MB-231 A443654
0.12
uM
LJP6
 2
I23
 72
hr
 1235 2120 4277 0.4956 0.3516
MDA-MB-231 A443654
0.12
uM
LJP6
 3
I23
 72
hr
 1235 2241 4583 0.4889 0.3699
MDA-MB-231 A443654
0.37
uM
LJP6
 1
I22
 72
hr
 1235 670 4355 0.1538 -0.2860
MDA-MB-231 A443654
0.37
uM
LJP6
 2
I22
 72
hr
 1235 735 4277 0.1718 -0.2519