LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 1
D03
 72
hr
 1235 636 4474 0.1421 -0.3009
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 2
D03
 72
hr
 1235 579 4578 0.1265 -0.3306
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 3
D03
 72
hr
 1235 744 4929 0.1509 -0.2246
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 1235 781 4355 0.1793 -0.2232
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 2
I02
 72
hr
 1235 413 4277 0.0966 -0.4577
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 1235 689 4583 0.1503 -0.2659
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 1
D02
 72
hr
 1235 639 4474 0.1428 -0.2991
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 2
D02
 72
hr
 1235 653 4578 0.1426 -0.2866
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 1235 723 4929 0.1467 -0.2356
MDA-MB-231 Dasatinib
10
uM
LJP6
 1
I01
 72
hr
 1235 468 4355 0.1074 -0.4140
MDA-MB-231 Dasatinib
10
uM
LJP6
 2
I01
 72
hr
 1235 229 4277 0.0535 -0.6099
MDA-MB-231 Dasatinib
10
uM
LJP6
 3
I01
 72
hr
 1235 613 4583 0.1337 -0.3099
MDA-MB-231 Dasatinib
10
uM
LJP5
 1
D01
 72
hr
 1235 562 4474 0.1256 -0.3460
MDA-MB-231 Dasatinib
10
uM
LJP5
 2
D01
 72
hr
 1235 527 4578 0.1151 -0.3631
MDA-MB-231 Dasatinib
10
uM
LJP5
 3
D01
 72
hr
 1235 827 4929 0.1678 -0.1824
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 1235 1369 4474 0.3059 0.0566
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 2
B18
 72
hr
 1235 1372 4578 0.2997 0.0568
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 1235 1406 4929 0.2852 0.0667
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 1235 1319 4474 0.2948 0.0357
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 1235 1388 4578 0.3032 0.0633
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 1235 1245 4929 0.2526 0.0037
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 1
B16
 72
hr
 1235 1515 4474 0.3386 0.1159
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 1235 1383 4578 0.3021 0.0613
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 1235 1434 4929 0.2909 0.0773
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 1235 1341 4474 0.2997 0.0449