LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 1235 1422 4578 0.3106 0.0770
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 1235 1292 4929 0.2621 0.0225
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 1235 1408 4474 0.3147 0.0727
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 1235 1557 4578 0.3401 0.1300
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 1235 1298 4929 0.2633 0.0248
MDA-MB-231 Tozasertib
10
uM
LJP5
 1
B13
 72
hr
 1235 1259 4474 0.2814 0.0100
MDA-MB-231 Tozasertib
10
uM
LJP5
 2
B13
 72
hr
 1235 1173 4578 0.2562 -0.0273
MDA-MB-231 Tozasertib
10
uM
LJP5
 3
B13
 72
hr
 1235 1353 4929 0.2745 0.0464
MDA-MB-231 Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 1235 4127 4355 0.9474 0.9415
MDA-MB-231 Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 1235 4458 4277 1.0422 1.0467
MDA-MB-231 Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 1235 4365 4583 0.9524 0.9490
MDA-MB-231 Imatinib
0.12
uM
LJP6
 1
N17
 72
hr
 1235 4241 4355 0.9736 0.9708
MDA-MB-231 Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 1235 4404 4277 1.0296 1.0328
MDA-MB-231 Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 1235 4333 4583 0.9454 0.9415
MDA-MB-231 Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 1235 4515 4355 1.0365 1.0399
MDA-MB-231 Imatinib
0.37
uM
LJP6
 2
N16
 72
hr
 1235 4501 4277 1.0523 1.0577
MDA-MB-231 Imatinib
0.37
uM
LJP6
 3
N16
 72
hr
 1235 4082 4583 0.8906 0.8811
MDA-MB-231 Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 1235 4337 4355 0.9957 0.9952
MDA-MB-231 Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 1235 4458 4277 1.0422 1.0467
MDA-MB-231 Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 1235 4044 4583 0.8823 0.8719
MDA-MB-231 Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 1235 4373 4355 1.0039 1.0043
MDA-MB-231 Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 1235 4376 4277 1.0231 1.0256
MDA-MB-231 Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 1235 4255 4583 0.9284 0.9229
MDA-MB-231 Imatinib
10
uM
LJP6
 1
N13
 72
hr
 1235 4117 4355 0.9452 0.9389
MDA-MB-231 Imatinib
10
uM
LJP6
 2
N13
 72
hr
 1235 4060 4277 0.9492 0.9426