LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Imatinib
10
uM
LJP6
 3
N13
 72
hr
 1235 4315 4583 0.9415 0.9372
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 1235 3862 4355 0.8866 0.8718
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 1235 3812 4277 0.8912 0.8754
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 1235 4002 4583 0.8732 0.8616
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 1235 3582 4355 0.8223 0.7959
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 1235 3603 4277 0.8423 0.8173
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 1235 3441 4583 0.7508 0.7186
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 1235 2924 4355 0.6713 0.6061
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 1235 3077 4277 0.7194 0.6640
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 1235 2739 4583 0.5976 0.5233
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 1235 2176 4355 0.4996 0.3651
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 1235 1678 4277 0.3923 0.1862
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 1235 1588 4583 0.3465 0.1417
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 1235 1280 4355 0.2939 0.0195
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 1235 1351 4277 0.3159 0.0509
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 1235 1219 4583 0.2660 -0.0073
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 1235 378 4355 0.0868 -0.4789
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 1235 432 4277 0.1010 -0.4439
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 1235 338 4583 0.0737 -0.4963
MDA-MB-231 CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 1235 569 4355 0.1306 -0.3474
MDA-MB-231 CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 1235 420 4277 0.0982 -0.4526
MDA-MB-231 CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 1235 613 4583 0.1337 -0.3099
MDA-MB-231 CGP60474
0.04
uM
LJP5
 1
F06
 72
hr
 1235 3038 4474 0.6789 0.6234
MDA-MB-231 CGP60474
0.04
uM
LJP5
 2
F06
 72
hr
 1235 3357 4578 0.7332 0.6970
MDA-MB-231 CGP60474
0.04
uM
LJP5
 3
F06
 72
hr
 1235 3518 4929 0.7137 0.6890