LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SB590885
10
uM
LJP5
 1
L13
 72
hr
 1235 258 4474 0.0577 -0.5700
MDA-MB-231 SB590885
10
uM
LJP5
 2
L13
 72
hr
 1235 281 4578 0.0614 -0.5434
MDA-MB-231 SB590885
10
uM
LJP5
 3
L13
 72
hr
 1235 302 4929 0.0613 -0.5064
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 1235 3614 4355 0.8297 0.8047
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 1235 3879 4277 0.9069 0.8938
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 1235 4108 4583 0.8963 0.8875
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 1235 3613 4355 0.8294 0.8044
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 1235 3623 4277 0.8470 0.8229
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 1235 3905 4583 0.8520 0.8376
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 1235 3463 4355 0.7950 0.7628
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 1235 3155 4277 0.7376 0.6875
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 1235 3208 4583 0.6999 0.6561
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 1235 2939 4355 0.6747 0.6107
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 1235 2846 4277 0.6654 0.5931
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 1235 3143 4583 0.6857 0.6382
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 1235 2899 4355 0.6655 0.5986
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 1235 2757 4277 0.6446 0.5651
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 1235 3058 4583 0.6672 0.6147
MDA-MB-231 Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 1235 1759 4355 0.4038 0.2143
MDA-MB-231 Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 1235 1922 4277 0.4493 0.2796
MDA-MB-231 Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 1235 1926 4583 0.4202 0.2644
MDA-MB-231 PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 1235 4028 4474 0.9002 0.8898
MDA-MB-231 PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 1235 4421 4578 0.9656 0.9633
MDA-MB-231 PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 1235 4689 4929 0.9513 0.9505
MDA-MB-231 PD184352
0.12
uM
LJP5
 1
L11
 72
hr
 1235 3788 4474 0.8465 0.8283