LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 3
B20
 72
hr
 1235 2921 4583 0.6373 0.5760
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 1
B19
 72
hr
 1235 624 4355 0.1433 -0.3134
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 2
B19
 72
hr
 1235 487 4277 0.1139 -0.4055
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 3
B19
 72
hr
 1235 786 4583 0.1715 -0.2129
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 1
I06
 72
hr
 1235 785 4355 0.1802 -0.2210
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 2
I06
 72
hr
 1235 799 4277 0.1868 -0.2162
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 3
I06
 72
hr
 1235 837 4583 0.1826 -0.1863
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 1
D06
 72
hr
 1235 2709 4474 0.6054 0.5262
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 2
D06
 72
hr
 1235 2660 4578 0.5810 0.5004
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 3
D06
 72
hr
 1235 2704 4929 0.5486 0.4804
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 1
I05
 72
hr
 1235 810 4355 0.1860 -0.2075
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 2
I05
 72
hr
 1235 784 4277 0.1833 -0.2244
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 3
I05
 72
hr
 1235 810 4583 0.1767 -0.2003
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 1
D05
 72
hr
 1235 1297 4474 0.2899 0.0263
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 2
D05
 72
hr
 1235 1366 4578 0.2984 0.0544
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 3
D05
 72
hr
 1235 1374 4929 0.2787 0.0545
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 1235 777 4355 0.1784 -0.2254
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 2
I04
 72
hr
 1235 756 4277 0.1767 -0.2400
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 1235 781 4583 0.1704 -0.2156
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 1235 819 4474 0.1830 -0.1988
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 1235 704 4578 0.1538 -0.2576
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 1235 848 4929 0.1720 -0.1720
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 1
I03
 72
hr
 1235 755 4355 0.1733 -0.2375
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 2
I03
 72
hr
 1235 488 4277 0.1141 -0.4048
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 3
I03
 72
hr
 1235 742 4583 0.1619 -0.2365