LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PF562271
10
uM
LJP6
 2
F13
 72
hr
 1235 442 4277 0.1033 -0.4368
MDA-MB-231 PF562271
10
uM
LJP6
 3
F13
 72
hr
 1235 501 4583 0.1093 -0.3797
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 1
E24
 72
hr
 1235 2399 4355 0.5507 0.4404
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 2
E24
 72
hr
 1235 2301 4277 0.5380 0.4148
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 3
E24
 72
hr
 1235 2478 4583 0.5407 0.4447
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 1
E23
 72
hr
 1235 1772 4355 0.4068 0.2193
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 2
E23
 72
hr
 1235 1603 4277 0.3748 0.1563
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 3
E23
 72
hr
 1235 1719 4583 0.3751 0.1906
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 1
E22
 72
hr
 1235 1084 4355 0.2489 -0.0696
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 2
E22
 72
hr
 1235 1173 4277 0.2742 -0.0288
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 3
E22
 72
hr
 1235 1245 4583 0.2716 0.0039
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 1
E21
 72
hr
 1235 846 4355 0.1942 -0.1883
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 2
E21
 72
hr
 1235 870 4277 0.2034 -0.1780
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 3
E21
 72
hr
 1235 1057 4583 0.2306 -0.0794
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 1
E20
 72
hr
 1235 696 4355 0.1598 -0.2709
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 2
E20
 72
hr
 1235 660 4277 0.1543 -0.2955
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 3
E20
 72
hr
 1235 715 4583 0.1560 -0.2513
MDA-MB-231 PHA-793887
10
uM
LJP6
 1
E19
 72
hr
 1235 351 4355 0.0806 -0.4998
MDA-MB-231 PHA-793887
10
uM
LJP6
 2
E19
 72
hr
 1235 428 4277 0.1001 -0.4468
MDA-MB-231 PHA-793887
10
uM
LJP6
 3
E19
 72
hr
 1235 416 4583 0.0908 -0.4378
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 1
F24
 72
hr
 1235 4063 4355 0.9328 0.9248
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 2
F24
 72
hr
 1235 4175 4277 0.9761 0.9731
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 3
F24
 72
hr
 1235 4079 4583 0.8900 0.8804
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 1
F23
 72
hr
 1235 3987 4355 0.9153 0.9049
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 2
F23
 72
hr
 1235 3727 4277 0.8713 0.8520