LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1235 1565 4355 0.3593 0.1387
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1235 1564 4277 0.3657 0.1405
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1235 1663 4583 0.3628 0.1700
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 1235 1704 4355 0.3912 0.1933
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 1235 1691 4277 0.3953 0.1913
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 1235 1696 4583 0.3700 0.1822
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1235 1571 4355 0.3607 0.1411
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1235 1544 4277 0.3610 0.1323
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1235 1541 4583 0.3362 0.1237
MDA-MB-231 WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 1235 1204 4355 0.2764 -0.0143
MDA-MB-231 WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 1235 1188 4277 0.2777 -0.0219
MDA-MB-231 WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 1235 1245 4583 0.2716 0.0039
MDA-MB-231 Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 1235 1433 4474 0.3202 0.0830
MDA-MB-231 Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 1235 1580 4578 0.3451 0.1388
MDA-MB-231 Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 1235 1549 4929 0.3142 0.1198
MDA-MB-231 Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 1235 1548 4474 0.3459 0.1289
MDA-MB-231 Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 1235 1527 4578 0.3335 0.1184
MDA-MB-231 Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 1235 1496 4929 0.3035 0.1004
MDA-MB-231 Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 1235 1713 4474 0.3828 0.1923
MDA-MB-231 Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 1235 1571 4578 0.3431 0.1354
MDA-MB-231 Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 1235 1341 4929 0.2721 0.0417
MDA-MB-231 Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 1235 1424 4474 0.3182 0.0793
MDA-MB-231 Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 1235 1381 4578 0.3016 0.0605
MDA-MB-231 Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 1235 1550 4929 0.3145 0.1201
MDA-MB-231 Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 1235 1436 4474 0.3209 0.0842