LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 2
P23
 72
hr
 1235 3875 4277 0.9059 0.8927
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 3
P23
 72
hr
 1235 4292 4583 0.9364 0.9317
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 1
P22
 72
hr
 1235 3887 4355 0.8924 0.8785
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 2
P22
 72
hr
 1235 3787 4277 0.8854 0.8686
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 3
P22
 72
hr
 1235 4127 4583 0.9004 0.8921
MDA-MB-231 XMD11-85h
1.11
uM
LJP6
 1
P21
 72
hr
 1235 3771 4355 0.8657 0.8474
MDA-MB-231 XMD11-85h
1.11
uM
LJP6
 2
P21
 72
hr
 1235 3623 4277 0.8470 0.8229
MDA-MB-231 XMD11-85h
1.11
uM
LJP6
 3
P21
 72
hr
 1235 4006 4583 0.8740 0.8625
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 1
P20
 72
hr
 1235 3526 4355 0.8095 0.7804
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 2
P20
 72
hr
 1235 3311 4277 0.7741 0.7336
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 3
P20
 72
hr
 1235 3896 4583 0.8500 0.8353
MDA-MB-231 XMD11-85h
10
uM
LJP6
 1
P19
 72
hr
 1235 1841 4355 0.4226 0.2452
MDA-MB-231 XMD11-85h
10
uM
LJP6
 2
P19
 72
hr
 1235 1798 4277 0.4204 0.2328
MDA-MB-231 XMD11-85h
10
uM
LJP6
 3
P19
 72
hr
 1235 1770 4583 0.3862 0.2092
MDA-MB-231 XMD16-144
0.04
uM
LJP5
 1
M12
 72
hr
 1235 1459 4474 0.3261 0.0935
MDA-MB-231 XMD16-144
0.04
uM
LJP5
 2
M12
 72
hr
 1235 1452 4578 0.3171 0.0890
MDA-MB-231 XMD16-144
0.04
uM
LJP5
 3
M12
 72
hr
 1235 1485 4929 0.3013 0.0963
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 1
M11
 72
hr
 1235 1300 4474 0.2905 0.0276
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 2
M11
 72
hr
 1235 1326 4578 0.2896 0.0379
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 3
M11
 72
hr
 1235 1447 4929 0.2936 0.0822
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 1
M10
 72
hr
 1235 1334 4474 0.2981 0.0420
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 2
M10
 72
hr
 1235 1469 4578 0.3208 0.0957
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 3
M10
 72
hr
 1235 1583 4929 0.3211 0.1320
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 1
M09
 72
hr
 1235 1326 4474 0.2963 0.0386
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 2
M09
 72
hr
 1235 1260 4578 0.2752 0.0103