LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 3
M09
 72
hr
 1235 1361 4929 0.2761 0.0495
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 1
M08
 72
hr
 1235 1143 4474 0.2554 -0.0412
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 2
M08
 72
hr
 1235 1162 4578 0.2538 -0.0321
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 3
M08
 72
hr
 1235 1236 4929 0.2508 0.0000
MDA-MB-231 XMD16-144
10
uM
LJP5
 1
M07
 72
hr
 1235 615 4474 0.1374 -0.3134
MDA-MB-231 XMD16-144
10
uM
LJP5
 2
M07
 72
hr
 1235 709 4578 0.1549 -0.2548
MDA-MB-231 XMD16-144
10
uM
LJP5
 3
M07
 72
hr
 1235 775 4929 0.1572 -0.2085
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 1
M24
 72
hr
 1235 3997 4474 0.8932 0.8820
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 2
M24
 72
hr
 1235 4041 4578 0.8826 0.8721
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 3
M24
 72
hr
 1235 4762 4929 0.9661 0.9657
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 1
M23
 72
hr
 1235 3917 4474 0.8754 0.8616
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 2
M23
 72
hr
 1235 4141 4578 0.9044 0.8964
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 3
M23
 72
hr
 1235 4773 4929 0.9683 0.9680
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 1235 4116 4474 0.9198 0.9120
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 2
M22
 72
hr
 1235 4120 4578 0.8998 0.8913
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 3
M22
 72
hr
 1235 4683 4929 0.9500 0.9493
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 1
M21
 72
hr
 1235 4066 4474 0.9087 0.8994
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 2
M21
 72
hr
 1235 4198 4578 0.9169 0.9102
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 3
M21
 72
hr
 1235 4703 4929 0.9541 0.9535
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 1
M20
 72
hr
 1235 4090 4474 0.9140 0.9054
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 2
M20
 72
hr
 1235 4396 4578 0.9601 0.9574
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 1235 4893 4929 0.9926 0.9926
MDA-MB-231 Erlotinib
10
uM
LJP5
 1
M19
 72
hr
 1235 2846 4474 0.6360 0.5673
MDA-MB-231 Erlotinib
10
uM
LJP5
 2
M19
 72
hr
 1235 3305 4578 0.7218 0.6831
MDA-MB-231 Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 1235 3611 4929 0.7326 0.7112