LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Foretinib
0.12
uM
LJP5
 3
H11
 72
hr
 1311 3187 5010 0.6360 0.5827
MDA-MB-231 Foretinib
0.37
uM
LJP5
 1
H10
 72
hr
 1311 1625 5128 0.3169 0.1150
MDA-MB-231 Foretinib
0.37
uM
LJP5
 2
H10
 72
hr
 1311 1749 5100 0.3429 0.1582
MDA-MB-231 Foretinib
0.37
uM
LJP5
 3
H10
 72
hr
 1311 1703 5010 0.3399 0.1446
MDA-MB-231 Foretinib
1.11
uM
LJP5
 1
H09
 72
hr
 1311 1409 5128 0.2748 0.0370
MDA-MB-231 Foretinib
1.11
uM
LJP5
 2
H09
 72
hr
 1311 1392 5100 0.2729 0.0308
MDA-MB-231 Foretinib
1.11
uM
LJP5
 3
H09
 72
hr
 1311 1440 5010 0.2874 0.0494
MDA-MB-231 Foretinib
3.33
uM
LJP5
 1
H08
 72
hr
 1311 1371 5128 0.2673 0.0227
MDA-MB-231 Foretinib
3.33
uM
LJP5
 2
H08
 72
hr
 1311 1307 5100 0.2563 -0.0018
MDA-MB-231 Foretinib
3.33
uM
LJP5
 3
H08
 72
hr
 1311 1287 5010 0.2568 -0.0098
MDA-MB-231 Foretinib
10
uM
LJP5
 1
H07
 72
hr
 1311 887 5128 0.1730 -0.1804
MDA-MB-231 Foretinib
10
uM
LJP5
 2
H07
 72
hr
 1311 751 5100 0.1473 -0.2477
MDA-MB-231 Foretinib
10
uM
LJP5
 3
H07
 72
hr
 1311 724 5010 0.1445 -0.2646
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 1
J06
 72
hr
 1311 4266 4870 0.8759 0.8648
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 2
J06
 72
hr
 1311 4168 4961 0.8400 0.8264
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 3
J06
 72
hr
 1311 4446 4973 0.8939 0.8867
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 1
J05
 72
hr
 1311 3397 4870 0.6975 0.6533
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 2
J05
 72
hr
 1311 3329 4961 0.6710 0.6246
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 3
J05
 72
hr
 1311 3493 4973 0.7023 0.6642
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 1
J04
 72
hr
 1311 2179 4870 0.4474 0.3076
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 2
J04
 72
hr
 1311 2276 4961 0.4587 0.3326
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 3
J04
 72
hr
 1311 2309 4973 0.4642 0.3419
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 1
J03
 72
hr
 1311 1210 4870 0.2485 -0.0418
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 2
J03
 72
hr
 1311 1221 4961 0.2461 -0.0367
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 3
J03
 72
hr
 1311 1392 4973 0.2799 0.0314