LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 1
J02
 72
hr
 1311 768 4870 0.1577 -0.2464
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 2
J02
 72
hr
 1311 736 4961 0.1483 -0.2600
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 3
J02
 72
hr
 1311 809 4973 0.1627 -0.2222
MDA-MB-231 AZD 5438
10
uM
LJP6
 1
J01
 72
hr
 1311 679 4870 0.1394 -0.2939
MDA-MB-231 AZD 5438
10
uM
LJP6
 2
J01
 72
hr
 1311 631 4961 0.1272 -0.3170
MDA-MB-231 AZD 5438
10
uM
LJP6
 3
J01
 72
hr
 1311 647 4973 0.1301 -0.3076
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 1311 5222 5128 1.0183 1.0185
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 1311 5359 5100 1.0508 1.0512
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 1311 5047 5010 1.0072 1.0074
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 1
I17
 72
hr
 1311 5282 5128 1.0300 1.0302
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 2
I17
 72
hr
 1311 5093 5100 0.9986 0.9986
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 1311 5386 5010 1.0749 1.0761
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 1
I16
 72
hr
 1311 4804 5128 0.9368 0.9347
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 2
I16
 72
hr
 1311 4552 5100 0.8926 0.8873
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 3
I16
 72
hr
 1311 4587 5010 0.9154 0.9106
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 1
I15
 72
hr
 1311 4480 5128 0.8736 0.8672
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 2
I15
 72
hr
 1311 4193 5100 0.8222 0.8098
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 3
I15
 72
hr
 1311 4319 5010 0.8619 0.8521
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 1311 3083 5128 0.6012 0.5441
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 1311 2622 5100 0.5141 0.4241
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 1311 2837 5010 0.5662 0.4903
MDA-MB-231 Pelitinib
10
uM
LJP5
 1
I13
 72
hr
 1311 1088 5128 0.2122 -0.0907
MDA-MB-231 Pelitinib
10
uM
LJP5
 2
I13
 72
hr
 1311 957 5100 0.1877 -0.1487
MDA-MB-231 Pelitinib
10
uM
LJP5
 3
I13
 72
hr
 1311 1112 5010 0.2219 -0.0819
MDA-MB-231 Luminespib
0.04
uM
LJP5
 1
H18
 72
hr
 1311 972 5128 0.1895 -0.1413