LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Mitoxantrone | 0.12 | uM | LJP5 | 2 | C23 | 72 | hr | 1311 | 1218 | 5100 | 0.2388 | -0.0371 |
| MDA-MB-231 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1311 | 1233 | 5010 | 0.2461 | -0.0315 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 1 | C22 | 72 | hr | 1311 | 1023 | 4870 | 0.2101 | -0.1231 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 2 | C22 | 72 | hr | 1311 | 952 | 4961 | 0.1919 | -0.1538 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 3 | C22 | 72 | hr | 1311 | 1002 | 4973 | 0.2015 | -0.1307 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP5 | 1 | C22 | 72 | hr | 1311 | 1066 | 5128 | 0.2079 | -0.1001 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP5 | 2 | C22 | 72 | hr | 1311 | 1021 | 5100 | 0.2002 | -0.1201 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP5 | 3 | C22 | 72 | hr | 1311 | 942 | 5010 | 0.1880 | -0.1574 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 1 | C21 | 72 | hr | 1311 | 954 | 4870 | 0.1959 | -0.1549 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 2 | C21 | 72 | hr | 1311 | 914 | 4961 | 0.1842 | -0.1716 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 3 | C21 | 72 | hr | 1311 | 845 | 4973 | 0.1699 | -0.2044 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 1 | C21 | 72 | hr | 1311 | 998 | 5128 | 0.1946 | -0.1297 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 2 | C21 | 72 | hr | 1311 | 940 | 5100 | 0.1843 | -0.1564 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 3 | C21 | 72 | hr | 1311 | 967 | 5010 | 0.1930 | -0.1459 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 1311 | 773 | 4870 | 0.1587 | -0.2438 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP6 | 2 | C20 | 72 | hr | 1311 | 704 | 4961 | 0.1419 | -0.2769 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP6 | 3 | C20 | 72 | hr | 1311 | 761 | 4973 | 0.1530 | -0.2466 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP5 | 1 | C20 | 72 | hr | 1311 | 851 | 5128 | 0.1659 | -0.1975 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP5 | 2 | C20 | 72 | hr | 1311 | 855 | 5100 | 0.1677 | -0.1963 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 1311 | 891 | 5010 | 0.1778 | -0.1813 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1311 | 631 | 4870 | 0.1296 | -0.3207 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1311 | 536 | 4961 | 0.1080 | -0.3727 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1311 | 514 | 4973 | 0.1033 | -0.3857 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1311 | 838 | 5128 | 0.1634 | -0.2037 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1311 | 764 | 5100 | 0.1498 | -0.2411 |