LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 1311 3694 5128 0.7203 0.6928
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 1311 3679 5100 0.7214 0.6929
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 1311 3636 5010 0.7256 0.6943
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 1311 3076 5128 0.5998 0.5423
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 1311 2959 5100 0.5802 0.5148
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 1311 2854 5010 0.5696 0.4949
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 1
K21
 72
hr
 1311 2422 5128 0.4723 0.3658
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 2
K21
 72
hr
 1311 2427 5100 0.4759 0.3690
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 3
K21
 72
hr
 1311 2520 5010 0.5029 0.4017
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 1
K20
 72
hr
 1311 2157 5128 0.4206 0.2877
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 2
K20
 72
hr
 1311 2069 5100 0.4057 0.2619
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 3
K20
 72
hr
 1311 2219 5010 0.4428 0.3124
MDA-MB-231 GDC-0980
10
uM
LJP5
 1
K19
 72
hr
 1311 1756 5128 0.3424 0.1599
MDA-MB-231 GDC-0980
10
uM
LJP5
 2
K19
 72
hr
 1311 1720 5100 0.3373 0.1484
MDA-MB-231 GDC-0980
10
uM
LJP5
 3
K19
 72
hr
 1311 1740 5010 0.3473 0.1573
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 1
C24
 72
hr
 1311 1108 4870 0.2275 -0.0853
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 1311 950 4961 0.1915 -0.1547
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 1311 1187 4973 0.2387 -0.0506
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 1
C24
 72
hr
 1311 1185 5128 0.2311 -0.0503
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 2
C24
 72
hr
 1311 1157 5100 0.2269 -0.0621
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 3
C24
 72
hr
 1311 1213 5010 0.2421 -0.0397
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 1311 1015 4870 0.2084 -0.1267
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 1311 1129 4961 0.2276 -0.0752
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 1311 1075 4973 0.2161 -0.0983
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 1
C23
 72
hr
 1311 1143 5128 0.2229 -0.0676