LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 1311 2003 5010 0.3997 0.2447
MDA-MB-231 Dactolisib
10
uM
LJP5
 1
M13
 72
hr
 1311 2226 5128 0.4341 0.3085
MDA-MB-231 Dactolisib
10
uM
LJP5
 2
M13
 72
hr
 1311 2026 5100 0.3973 0.2485
MDA-MB-231 Dactolisib
10
uM
LJP5
 3
M13
 72
hr
 1311 2265 5010 0.4520 0.3264
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 1311 5131 5128 1.0005 1.0005
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 1311 5093 5100 0.9986 0.9986
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 1311 5327 5010 1.0631 1.0643
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 1311 5301 5128 1.0337 1.0339
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 1311 4873 5100 0.9555 0.9541
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 1311 5378 5010 1.0733 1.0745
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 1311 5236 5128 1.0210 1.0212
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 1311 4573 5100 0.8967 0.8917
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1311 5167 5010 1.0312 1.0320
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 1311 5059 5128 0.9865 0.9862
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 1311 4607 5100 0.9033 0.8989
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 1311 4980 5010 0.9938 0.9936
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 1311 4525 5128 0.8824 0.8767
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 1311 4546 5100 0.8914 0.8860
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 1311 4599 5010 0.9178 0.9132
MDA-MB-231 Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 1311 3606 5128 0.7032 0.6721
MDA-MB-231 Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 1311 3384 5100 0.6635 0.6222
MDA-MB-231 Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 1311 3505 5010 0.6995 0.6625
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 1311 4159 5128 0.8110 0.7979
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 1311 3943 5100 0.7731 0.7538
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 3
K24
 72
hr
 1311 4021 5010 0.8025 0.7848