LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Y39983
10
uM
LJP6
 2
P01
 72
hr
 1311 804 4961 0.1620 -0.2251
MDA-MB-231 Y39983
10
uM
LJP6
 3
P01
 72
hr
 1311 684 4973 0.1375 -0.2873
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 1311 5171 4870 1.0618 1.0643
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 1311 4970 4961 1.0017 1.0018
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 1311 5395 4973 1.0847 1.0864
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 1311 5119 4870 1.0511 1.0533
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 1311 5162 4961 1.0404 1.0417
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 1311 5114 4973 1.0282 1.0291
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 1
H04
 72
hr
 1311 5030 4870 1.0328 1.0344
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 2
H04
 72
hr
 1311 4763 4961 0.9600 0.9579
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 3
H04
 72
hr
 1311 4858 4973 0.9767 0.9757
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 1
H03
 72
hr
 1311 4686 4870 0.9622 0.9597
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 2
H03
 72
hr
 1311 4729 4961 0.9531 0.9506
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 3
H03
 72
hr
 1311 4900 4973 0.9852 0.9845
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 1311 4450 4870 0.9137 0.9069
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 1311 4649 4961 0.9370 0.9333
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 1311 4756 4973 0.9562 0.9540
MDA-MB-231 Nintedanib
10
uM
LJP6
 1
H01
 72
hr
 1311 3811 4870 0.7825 0.7569
MDA-MB-231 Nintedanib
10
uM
LJP6
 2
H01
 72
hr
 1311 4191 4961 0.8447 0.8316
MDA-MB-231 Nintedanib
10
uM
LJP6
 3
H01
 72
hr
 1311 4890 4973 0.9832 0.9824
MDA-MB-231 Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 1311 4636 5128 0.9040 0.9000
MDA-MB-231 Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 1311 4446 5100 0.8718 0.8647
MDA-MB-231 Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 1311 4339 5010 0.8659 0.8565
MDA-MB-231 Foretinib
0.12
uM
LJP5
 1
H11
 72
hr
 1311 3336 5128 0.6505 0.6073
MDA-MB-231 Foretinib
0.12
uM
LJP5
 2
H11
 72
hr
 1311 3416 5100 0.6698 0.6300