LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 1
E24
 72
hr
 1311 5089 5128 0.9923 0.9922
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 2
E24
 72
hr
 1311 4746 5100 0.9306 0.9279
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 1311 4739 5010 0.9458 0.9431
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 1311 4899 5128 0.9553 0.9540
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 1311 4841 5100 0.9492 0.9475
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 1311 4739 5010 0.9458 0.9431
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 1311 3433 5128 0.6694 0.6309
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 1311 3508 5100 0.6878 0.6523
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 1311 3523 5010 0.7031 0.6669
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 1311 3368 5128 0.6567 0.6151
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 1311 2960 5100 0.5804 0.5150
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 1311 3284 5010 0.6554 0.6074
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 1311 2514 5128 0.4902 0.3920
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 1311 2485 5100 0.4873 0.3856
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 1311 2371 5010 0.4732 0.3582
MDA-MB-231 Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 1311 2025 5128 0.3949 0.2470
MDA-MB-231 Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 1311 2095 5100 0.4108 0.2700
MDA-MB-231 Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 1311 1963 5010 0.3918 0.2318
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 1311 4684 5128 0.9134 0.9099
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 1311 4674 5100 0.9165 0.9129
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 1311 4931 5010 0.9841 0.9835
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 1311 4729 5128 0.9221 0.9193
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 2
F23
 72
hr
 1311 4650 5100 0.9118 0.9079
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 3
F23
 72
hr
 1311 4788 5010 0.9555 0.9535
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 1
F22
 72
hr
 1311 4804 5128 0.9368 0.9347