LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 2
F22
 72
hr
 1311 4446 5100 0.8718 0.8647
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 3
F22
 72
hr
 1311 4648 5010 0.9276 0.9237
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 1
F21
 72
hr
 1311 4565 5128 0.8902 0.8851
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 2
F21
 72
hr
 1311 4602 5100 0.9024 0.8978
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 3
F21
 72
hr
 1311 4825 5010 0.9629 0.9613
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 1
F20
 72
hr
 1311 4936 5128 0.9625 0.9615
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 2
F20
 72
hr
 1311 4930 5100 0.9667 0.9657
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 3
F20
 72
hr
 1311 4982 5010 0.9942 0.9940
MDA-MB-231 GSK 690693
10
uM
LJP5
 1
F19
 72
hr
 1311 4734 5128 0.9231 0.9203
MDA-MB-231 GSK 690693
10
uM
LJP5
 2
F19
 72
hr
 1311 4445 5100 0.8716 0.8645
MDA-MB-231 GSK 690693
10
uM
LJP5
 3
F19
 72
hr
 1311 4759 5010 0.9497 0.9474
MDA-MB-231 SNS-032
0.04
uM
LJP6
 1
H18
 72
hr
 1311 2437 4870 0.5004 0.3872
MDA-MB-231 SNS-032
0.04
uM
LJP6
 2
H18
 72
hr
 1311 2409 4961 0.4855 0.3726
MDA-MB-231 SNS-032
0.04
uM
LJP6
 3
H18
 72
hr
 1311 2204 4973 0.4431 0.3098
MDA-MB-231 SNS-032
0.12
uM
LJP6
 1
H17
 72
hr
 1311 817 4870 0.1678 -0.2213
MDA-MB-231 SNS-032
0.12
uM
LJP6
 2
H17
 72
hr
 1311 824 4961 0.1661 -0.2151
MDA-MB-231 SNS-032
0.12
uM
LJP6
 3
H17
 72
hr
 1311 798 4973 0.1604 -0.2278
MDA-MB-231 SNS-032
0.37
uM
LJP6
 1
H16
 72
hr
 1311 732 4870 0.1503 -0.2653
MDA-MB-231 SNS-032
0.37
uM
LJP6
 2
H16
 72
hr
 1311 721 4961 0.1453 -0.2679
MDA-MB-231 SNS-032
0.37
uM
LJP6
 3
H16
 72
hr
 1311 718 4973 0.1444 -0.2690
MDA-MB-231 SNS-032
1.11
uM
LJP6
 1
H15
 72
hr
 1311 789 4870 0.1620 -0.2356
MDA-MB-231 SNS-032
1.11
uM
LJP6
 2
H15
 72
hr
 1311 765 4961 0.1542 -0.2449
MDA-MB-231 SNS-032
1.11
uM
LJP6
 3
H15
 72
hr
 1311 735 4973 0.1478 -0.2601
MDA-MB-231 SNS-032
3.33
uM
LJP6
 1
H14
 72
hr
 1311 817 4870 0.1678 -0.2213
MDA-MB-231 SNS-032
3.33
uM
LJP6
 2
H14
 72
hr
 1311 822 4961 0.1657 -0.2161