LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 1311 774 4973 0.1556 -0.2399
MDA-MB-231 SNS-032
10
uM
LJP6
 1
H13
 72
hr
 1311 775 4870 0.1591 -0.2428
MDA-MB-231 SNS-032
10
uM
LJP6
 2
H13
 72
hr
 1311 805 4961 0.1622 -0.2246
MDA-MB-231 SNS-032
10
uM
LJP6
 3
H13
 72
hr
 1311 875 4973 0.1759 -0.1899
MDA-MB-231 Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 1311 4425 4870 0.9086 0.9012
MDA-MB-231 Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 1311 4302 4961 0.8671 0.8567
MDA-MB-231 Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 1311 4401 4973 0.8848 0.8767
MDA-MB-231 Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 1311 4298 4870 0.8825 0.8722
MDA-MB-231 Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 1311 4336 4961 0.8739 0.8644
MDA-MB-231 Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 1311 4473 4973 0.8993 0.8926
MDA-MB-231 Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 1311 3458 4870 0.7100 0.6690
MDA-MB-231 Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 1311 3817 4961 0.7693 0.7446
MDA-MB-231 Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 1311 3699 4973 0.7437 0.7146
MDA-MB-231 Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 1311 3413 4870 0.7008 0.6575
MDA-MB-231 Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 1311 3423 4961 0.6899 0.6483
MDA-MB-231 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 1311 3493 4973 0.7023 0.6642
MDA-MB-231 Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 1311 2884 4870 0.5922 0.5163
MDA-MB-231 Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 1311 2836 4961 0.5716 0.4944
MDA-MB-231 Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 1311 2715 4973 0.5459 0.4598
MDA-MB-231 Afatinib
10
uM
LJP6
 1
G19
 72
hr
 1311 849 4870 0.1743 -0.2054
MDA-MB-231 Afatinib
10
uM
LJP6
 2
G19
 72
hr
 1311 826 4961 0.1665 -0.2141
MDA-MB-231 Afatinib
10
uM
LJP6
 3
G19
 72
hr
 1311 751 4973 0.1510 -0.2518
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 1311 4260 4870 0.8747 0.8634
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 1311 4095 4961 0.8253 0.8096
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 3
H24
 72
hr
 1311 4317 4973 0.8680 0.8580