LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Geldanamycin
10
uM
LJP5
 2
O01
 72
hr
 1311 800 5100 0.1569 -0.2231
MDA-MB-231 Geldanamycin
10
uM
LJP5
 3
O01
 72
hr
 1311 698 5010 0.1393 -0.2784
MDA-MB-231 YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 1311 5418 5128 1.0565 1.0566
MDA-MB-231 YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 1311 5239 5100 1.0273 1.0276
MDA-MB-231 YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 1311 5472 5010 1.0920 1.0932
MDA-MB-231 YM 201636
0.12
uM
LJP5
 1
N11
 72
hr
 1311 5270 5128 1.0276 1.0279
MDA-MB-231 YM 201636
0.12
uM
LJP5
 2
N11
 72
hr
 1311 4629 5100 0.9077 0.9035
MDA-MB-231 YM 201636
0.12
uM
LJP5
 3
N11
 72
hr
 1311 5405 5010 1.0787 1.0799
MDA-MB-231 YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 1311 4746 5128 0.9254 0.9228
MDA-MB-231 YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 1311 4566 5100 0.8953 0.8902
MDA-MB-231 YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 1311 4711 5010 0.9402 0.9372
MDA-MB-231 YM 201636
1.11
uM
LJP5
 1
N09
 72
hr
 1311 4138 5128 0.8069 0.7933
MDA-MB-231 YM 201636
1.11
uM
LJP5
 2
N09
 72
hr
 1311 3745 5100 0.7343 0.7083
MDA-MB-231 YM 201636
1.11
uM
LJP5
 3
N09
 72
hr
 1311 4208 5010 0.8398 0.8273
MDA-MB-231 YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 1311 3909 5128 0.7622 0.7422
MDA-MB-231 YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 1311 3594 5100 0.7047 0.6728
MDA-MB-231 YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 1311 3715 5010 0.7414 0.7133
MDA-MB-231 YM 201636
10
uM
LJP5
 1
N07
 72
hr
 1311 1348 5128 0.2629 0.0140
MDA-MB-231 YM 201636
10
uM
LJP5
 2
N07
 72
hr
 1311 1327 5100 0.2602 0.0059
MDA-MB-231 YM 201636
10
uM
LJP5
 3
N07
 72
hr
 1311 1484 5010 0.2962 0.0659
MDA-MB-231 TWS119
0.04
uM
LJP5
 1
M06
 72
hr
 1311 5178 5128 1.0097 1.0098
MDA-MB-231 TWS119
0.04
uM
LJP5
 2
M06
 72
hr
 1311 4922 5100 0.9651 0.9641
MDA-MB-231 TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 1311 5487 5010 1.0950 1.0961
MDA-MB-231 TWS119
0.12
uM
LJP5
 1
M05
 72
hr
 1311 5048 5128 0.9843 0.9840
MDA-MB-231 TWS119
0.12
uM
LJP5
 2
M05
 72
hr
 1311 4547 5100 0.8916 0.8862