LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 1311 4945 5100 0.9696 0.9687
MDA-MB-231 PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 1311 5346 5010 1.0669 1.0681
MDA-MB-231 PIK-93
1.11
uM
LJP5
 1
K15
 72
hr
 1311 4613 5128 0.8995 0.8952
MDA-MB-231 PIK-93
1.11
uM
LJP5
 2
K15
 72
hr
 1311 4569 5100 0.8959 0.8909
MDA-MB-231 PIK-93
1.11
uM
LJP5
 3
K15
 72
hr
 1311 5157 5010 1.0292 1.0300
MDA-MB-231 PIK-93
3.33
uM
LJP5
 1
K14
 72
hr
 1311 4039 5128 0.7876 0.7714
MDA-MB-231 PIK-93
3.33
uM
LJP5
 2
K14
 72
hr
 1311 3920 5100 0.7686 0.7486
MDA-MB-231 PIK-93
3.33
uM
LJP5
 3
K14
 72
hr
 1311 4262 5010 0.8506 0.8394
MDA-MB-231 PIK-93
10
uM
LJP5
 1
K13
 72
hr
 1311 2098 5128 0.4091 0.2697
MDA-MB-231 PIK-93
10
uM
LJP5
 2
K13
 72
hr
 1311 1943 5100 0.3810 0.2221
MDA-MB-231 PIK-93
10
uM
LJP5
 3
K13
 72
hr
 1311 2186 5010 0.4363 0.3023
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 1311 2850 5128 0.5557 0.4836
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 1311 2647 5100 0.5190 0.4310
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 1311 3012 5010 0.6011 0.5371
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 1311 2443 5128 0.4764 0.3718
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 1311 2360 5100 0.4628 0.3496
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 1311 2403 5010 0.4796 0.3676
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 1
M16
 72
hr
 1311 2132 5128 0.4157 0.2801
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 2
M16
 72
hr
 1311 1862 5100 0.3651 0.1958
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 3
M16
 72
hr
 1311 2116 5010 0.4223 0.2806
MDA-MB-231 Dactolisib
1.11
uM
LJP5
 1
M15
 72
hr
 1311 2163 5128 0.4218 0.2895
MDA-MB-231 Dactolisib
1.11
uM
LJP5
 2
M15
 72
hr
 1311 1897 5100 0.3720 0.2072
MDA-MB-231 Dactolisib
1.11
uM
LJP5
 3
M15
 72
hr
 1311 2192 5010 0.4375 0.3042
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 1311 2154 5128 0.4200 0.2868
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 1311 2057 5100 0.4033 0.2582