LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Mitoxantrone
10
uM
LJP5
 3
C19
 72
hr
 1311 758 5010 0.1513 -0.2470
MDA-MB-231 Radicicol
0.04
uM
LJP6
 1
K12
 72
hr
 1311 5094 4870 1.0459 1.0480
MDA-MB-231 Radicicol
0.04
uM
LJP6
 2
K12
 72
hr
 1311 5232 4961 1.0545 1.0561
MDA-MB-231 Radicicol
0.04
uM
LJP6
 3
K12
 72
hr
 1311 5031 4973 1.0115 1.0119
MDA-MB-231 Radicicol
0.04
uM
LJP5
 1
K12
 72
hr
 1311 5423 5128 1.0575 1.0576
MDA-MB-231 Radicicol
0.04
uM
LJP5
 2
K12
 72
hr
 1311 5293 5100 1.0378 1.0383
MDA-MB-231 Radicicol
0.04
uM
LJP5
 3
K12
 72
hr
 1311 5332 5010 1.0641 1.0653
MDA-MB-231 Radicicol
0.12
uM
LJP6
 1
K11
 72
hr
 1311 4385 4870 0.9004 0.8921
MDA-MB-231 Radicicol
0.12
uM
LJP6
 2
K11
 72
hr
 1311 4325 4961 0.8717 0.8619
MDA-MB-231 Radicicol
0.12
uM
LJP6
 3
K11
 72
hr
 1311 4274 4973 0.8593 0.8484
MDA-MB-231 Radicicol
0.12
uM
LJP5
 1
K11
 72
hr
 1311 4378 5128 0.8537 0.8455
MDA-MB-231 Radicicol
0.12
uM
LJP5
 2
K11
 72
hr
 1311 4012 5100 0.7867 0.7694
MDA-MB-231 Radicicol
0.12
uM
LJP5
 3
K11
 72
hr
 1311 4414 5010 0.8809 0.8730
MDA-MB-231 Radicicol
0.37
uM
LJP6
 1
K10
 72
hr
 1311 2371 4870 0.4868 0.3672
MDA-MB-231 Radicicol
0.37
uM
LJP6
 2
K10
 72
hr
 1311 2501 4961 0.5041 0.3997
MDA-MB-231 Radicicol
0.37
uM
LJP6
 3
K10
 72
hr
 1311 2578 4973 0.5183 0.4210
MDA-MB-231 Radicicol
0.37
uM
LJP5
 1
K10
 72
hr
 1311 2664 5128 0.5195 0.4336
MDA-MB-231 Radicicol
0.37
uM
LJP5
 2
K10
 72
hr
 1311 2230 5100 0.4373 0.3111
MDA-MB-231 Radicicol
0.37
uM
LJP5
 3
K10
 72
hr
 1311 2601 5010 0.5191 0.4248
MDA-MB-231 Radicicol
1.11
uM
LJP6
 1
K09
 72
hr
 1311 1681 4870 0.3452 0.1401
MDA-MB-231 Radicicol
1.11
uM
LJP6
 2
K09
 72
hr
 1311 1488 4961 0.2999 0.0679
MDA-MB-231 Radicicol
1.11
uM
LJP6
 3
K09
 72
hr
 1311 1651 4973 0.3319 0.1271
MDA-MB-231 Radicicol
1.11
uM
LJP5
 1
K09
 72
hr
 1311 1567 5128 0.3056 0.0946
MDA-MB-231 Radicicol
1.11
uM
LJP5
 2
K09
 72
hr
 1311 1479 5100 0.2900 0.0632
MDA-MB-231 Radicicol
1.11
uM
LJP5
 3
K09
 72
hr
 1311 1734 5010 0.3461 0.1553