LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PD184352
0.12
uM
LJP5
 1
L11
 72
hr
 1311 4514 5128 0.8802 0.8744
MDA-MB-231 PD184352
0.12
uM
LJP5
 2
L11
 72
hr
 1311 4185 5100 0.8206 0.8080
MDA-MB-231 PD184352
0.12
uM
LJP5
 3
L11
 72
hr
 1311 4326 5010 0.8633 0.8536
MDA-MB-231 PD184352
0.37
uM
LJP5
 1
L10
 72
hr
 1311 4090 5128 0.7975 0.7827
MDA-MB-231 PD184352
0.37
uM
LJP5
 2
L10
 72
hr
 1311 3855 5100 0.7559 0.7338
MDA-MB-231 PD184352
0.37
uM
LJP5
 3
L10
 72
hr
 1311 4104 5010 0.8190 0.8038
MDA-MB-231 PD184352
1.11
uM
LJP5
 1
L09
 72
hr
 1311 3482 5128 0.6790 0.6427
MDA-MB-231 PD184352
1.11
uM
LJP5
 2
L09
 72
hr
 1311 3245 5100 0.6363 0.5878
MDA-MB-231 PD184352
1.11
uM
LJP5
 3
L09
 72
hr
 1311 3483 5010 0.6951 0.6571
MDA-MB-231 PD184352
3.33
uM
LJP5
 1
L08
 72
hr
 1311 2860 5128 0.5577 0.4863
MDA-MB-231 PD184352
3.33
uM
LJP5
 2
L08
 72
hr
 1311 2879 5100 0.5645 0.4937
MDA-MB-231 PD184352
3.33
uM
LJP5
 3
L08
 72
hr
 1311 2951 5010 0.5889 0.5209
MDA-MB-231 PD184352
10
uM
LJP5
 1
L07
 72
hr
 1311 1870 5128 0.3646 0.1975
MDA-MB-231 PD184352
10
uM
LJP5
 2
L07
 72
hr
 1311 1896 5100 0.3718 0.2069
MDA-MB-231 PD184352
10
uM
LJP5
 3
L07
 72
hr
 1311 1867 5010 0.3726 0.2003
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 1
K06
 72
hr
 1311 5312 5128 1.0358 1.0361
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 2
K06
 72
hr
 1311 4914 5100 0.9635 0.9624
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 3
K06
 72
hr
 1311 5256 5010 1.0489 1.0500
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 1
K05
 72
hr
 1311 5300 5128 1.0335 1.0338
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 2
K05
 72
hr
 1311 4998 5100 0.9800 0.9795
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 3
K05
 72
hr
 1311 5122 5010 1.0222 1.0228
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 1
K04
 72
hr
 1311 5382 5128 1.0495 1.0497
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 2
K04
 72
hr
 1311 4874 5100 0.9557 0.9543
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 3
K04
 72
hr
 1311 5238 5010 1.0453 1.0464
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 1
K03
 72
hr
 1311 5050 5128 0.9847 0.9844