LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 1311 4752 5100 0.9318 0.9291
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 3
K03
 72
hr
 1311 4889 5010 0.9757 0.9747
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 1
K02
 72
hr
 1311 4860 5128 0.9477 0.9461
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 1311 4387 5100 0.8602 0.8520
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 1311 4162 5010 0.8306 0.8169
MDA-MB-231 PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 1311 4239 5128 0.8266 0.8154
MDA-MB-231 PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 1311 3400 5100 0.6667 0.6261
MDA-MB-231 PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 1311 3399 5010 0.6783 0.6363
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 1311 4529 4870 0.9299 0.9247
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 1311 4446 4961 0.8961 0.8889
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 1311 4512 4973 0.9072 0.9012
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 1311 4475 4870 0.9189 0.9125
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 1311 4635 4961 0.9342 0.9303
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 1311 4968 4973 0.9988 0.9988
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 1311 4581 4870 0.9406 0.9363
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 1311 4754 4961 0.9582 0.9560
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 1311 4909 4973 0.9870 0.9864
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 1311 4523 4870 0.9287 0.9234
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 1311 4664 4961 0.9400 0.9366
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 1311 4763 4973 0.9576 0.9555
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 1311 4470 4870 0.9178 0.9114
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 1311 4682 4961 0.9436 0.9405
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 1311 4763 4973 0.9576 0.9555
MDA-MB-231 Lapatinib
10
uM
LJP6
 1
M19
 72
hr
 1311 3429 4870 0.7041 0.6616
MDA-MB-231 Lapatinib
10
uM
LJP6
 2
M19
 72
hr
 1311 3187 4961 0.6423 0.5881