LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Lapatinib
10
uM
LJP6
 3
M19
 72
hr
 1311 3516 4973 0.7069 0.6699
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 1311 4577 4870 0.9398 0.9354
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 1311 3899 4961 0.7858 0.7640
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 1311 4308 4973 0.8661 0.8560
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 1311 4267 4870 0.8761 0.8650
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 1311 3920 4961 0.7901 0.7689
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 1311 4261 4973 0.8567 0.8454
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 1311 4414 4870 0.9063 0.8987
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 1311 3921 4961 0.7903 0.7692
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 1311 4415 4973 0.8877 0.8798
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 1311 4244 4870 0.8714 0.8597
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 1311 3939 4961 0.7939 0.7734
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 1311 4359 4973 0.8764 0.8674
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 1
L14
 72
hr
 1311 4362 4870 0.8957 0.8869
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 2
L14
 72
hr
 1311 4048 4961 0.8159 0.7988
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 3
L14
 72
hr
 1311 4369 4973 0.8784 0.8696
MDA-MB-231 Sirolimus
10
uM
LJP6
 1
L13
 72
hr
 1311 4361 4870 0.8954 0.8866
MDA-MB-231 Sirolimus
10
uM
LJP6
 2
L13
 72
hr
 1311 4148 4961 0.8360 0.8218
MDA-MB-231 Sirolimus
10
uM
LJP6
 3
L13
 72
hr
 1311 4388 4973 0.8822 0.8738
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 1311 4617 4870 0.9480 0.9444
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 1311 4265 4961 0.8596 0.8484
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 1311 4439 4973 0.8925 0.8851
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 1
M17
 72
hr
 1311 4259 4870 0.8745 0.8632
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 2
M17
 72
hr
 1311 3899 4961 0.7858 0.7640
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 3
M17
 72
hr
 1311 4382 4973 0.8810 0.8725