LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PF562271
10
uM
LJP6
 1
F13
 72
hr
 1311 920 4870 0.1889 -0.1709
MDA-MB-231 PF562271
10
uM
LJP6
 2
F13
 72
hr
 1311 865 4961 0.1743 -0.1950
MDA-MB-231 PF562271
10
uM
LJP6
 3
F13
 72
hr
 1311 864 4973 0.1737 -0.1952
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 1
E24
 72
hr
 1311 2232 4870 0.4583 0.3243
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 2
E24
 72
hr
 1311 2413 4961 0.4863 0.3738
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 3
E24
 72
hr
 1311 2326 4973 0.4677 0.3470
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 1
E23
 72
hr
 1311 2124 4870 0.4361 0.2900
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 2
E23
 72
hr
 1311 2114 4961 0.4261 0.2823
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 3
E23
 72
hr
 1311 2177 4973 0.4377 0.3014
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 1
E22
 72
hr
 1311 1362 4870 0.2797 0.0201
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 2
E22
 72
hr
 1311 1569 4961 0.3162 0.0978
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 3
E22
 72
hr
 1311 1517 4973 0.3050 0.0785
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 1
E21
 72
hr
 1311 1228 4870 0.2521 -0.0342
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 2
E21
 72
hr
 1311 1368 4961 0.2757 0.0221
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 3
E21
 72
hr
 1311 1201 4973 0.2415 -0.0448
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 1
E20
 72
hr
 1311 1029 4870 0.2113 -0.1204
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 2
E20
 72
hr
 1311 1048 4961 0.2112 -0.1104
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 3
E20
 72
hr
 1311 1088 4973 0.2188 -0.0927
MDA-MB-231 PHA-793887
10
uM
LJP6
 1
E19
 72
hr
 1311 748 4870 0.1536 -0.2568
MDA-MB-231 PHA-793887
10
uM
LJP6
 2
E19
 72
hr
 1311 753 4961 0.1518 -0.2511
MDA-MB-231 PHA-793887
10
uM
LJP6
 3
E19
 72
hr
 1311 727 4973 0.1462 -0.2643
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 1
F24
 72
hr
 1311 4107 4870 0.8433 0.8278
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 2
F24
 72
hr
 1311 4341 4961 0.8749 0.8655
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 3
F24
 72
hr
 1311 4625 4973 0.9299 0.9258
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 1
F23
 72
hr
 1311 4231 4870 0.8688 0.8567