LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 2
A24
 72
hr
 1311 4060 5100 0.7961 0.7802
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 3
A24
 72
hr
 1311 4288 5010 0.8557 0.8452
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 1
A23
 72
hr
 1311 4595 5128 0.8960 0.8914
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 2
A23
 72
hr
 1311 4441 5100 0.8708 0.8636
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 3
A23
 72
hr
 1311 4644 5010 0.9268 0.9229
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 1311 4380 5128 0.8541 0.8459
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 1311 4031 5100 0.7904 0.7737
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 1311 3998 5010 0.7979 0.7796
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 1
A21
 72
hr
 1311 4104 5128 0.8003 0.7858
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 2
A21
 72
hr
 1311 3697 5100 0.7249 0.6971
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 3
A21
 72
hr
 1311 3736 5010 0.7456 0.7183
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 1
A20
 72
hr
 1311 2233 5128 0.4354 0.3106
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 2
A20
 72
hr
 1311 2176 5100 0.4267 0.2948
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 3
A20
 72
hr
 1311 2209 5010 0.4408 0.3094
MDA-MB-231 Crizotinib
10
uM
LJP5
 1
A19
 72
hr
 1311 1278 5128 0.2492 -0.0132
MDA-MB-231 Crizotinib
10
uM
LJP5
 2
A19
 72
hr
 1311 1222 5100 0.2396 -0.0355
MDA-MB-231 Crizotinib
10
uM
LJP5
 3
A19
 72
hr
 1311 1242 5010 0.2479 -0.0279
MDA-MB-231 BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 1311 4706 4870 0.9663 0.9641
MDA-MB-231 BMS345541
0.04
uM
LJP6
 2
D06
 72
hr
 1311 5148 4961 1.0376 1.0388
MDA-MB-231 BMS345541
0.04
uM
LJP6
 3
D06
 72
hr
 1311 4891 4973 0.9834 0.9826
MDA-MB-231 BMS345541
0.12
uM
LJP6
 1
D05
 72
hr
 1311 4546 4870 0.9334 0.9285
MDA-MB-231 BMS345541
0.12
uM
LJP6
 2
D05
 72
hr
 1311 4464 4961 0.8997 0.8929
MDA-MB-231 BMS345541
0.12
uM
LJP6
 3
D05
 72
hr
 1311 4944 4973 0.9940 0.9938
MDA-MB-231 BMS345541
0.37
uM
LJP6
 1
D04
 72
hr
 1311 4589 4870 0.9423 0.9381
MDA-MB-231 BMS345541
0.37
uM
LJP6
 2
D04
 72
hr
 1311 4664 4961 0.9400 0.9366