LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 BMS345541
0.37
uM
LJP6
 3
D04
 72
hr
 1311 4452 4973 0.8951 0.8880
MDA-MB-231 BMS345541
1.11
uM
LJP6
 1
D03
 72
hr
 1311 3861 4870 0.7928 0.7691
MDA-MB-231 BMS345541
1.11
uM
LJP6
 2
D03
 72
hr
 1311 3700 4961 0.7457 0.7165
MDA-MB-231 BMS345541
1.11
uM
LJP6
 3
D03
 72
hr
 1311 3823 4973 0.7686 0.7442
MDA-MB-231 BMS345541
3.33
uM
LJP6
 1
D02
 72
hr
 1311 2375 4870 0.4877 0.3685
MDA-MB-231 BMS345541
3.33
uM
LJP6
 2
D02
 72
hr
 1311 2577 4961 0.5194 0.4217
MDA-MB-231 BMS345541
3.33
uM
LJP6
 3
D02
 72
hr
 1311 2422 4973 0.4870 0.3757
MDA-MB-231 BMS345541
10
uM
LJP6
 1
D01
 72
hr
 1311 752 4870 0.1544 -0.2547
MDA-MB-231 BMS345541
10
uM
LJP6
 2
D01
 72
hr
 1311 763 4961 0.1538 -0.2460
MDA-MB-231 BMS345541
10
uM
LJP6
 3
D01
 72
hr
 1311 820 4973 0.1649 -0.2168
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 1
C12
 72
hr
 1311 4719 4870 0.9690 0.9669
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 2
C12
 72
hr
 1311 5014 4961 1.0106 1.0110
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 3
C12
 72
hr
 1311 4583 4973 0.9214 0.9167
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 1
C11
 72
hr
 1311 3949 4870 0.8109 0.7903
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 2
C11
 72
hr
 1311 4802 4961 0.9678 0.9662
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 3
C11
 72
hr
 1311 4016 4973 0.8074 0.7895
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 1
C10
 72
hr
 1311 3980 4870 0.8172 0.7977
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 2
C10
 72
hr
 1311 4579 4961 0.9229 0.9181
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 3
C10
 72
hr
 1311 3871 4973 0.7783 0.7556
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 1
C09
 72
hr
 1311 4007 4870 0.8228 0.8041
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 2
C09
 72
hr
 1311 4368 4961 0.8804 0.8715
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 3
C09
 72
hr
 1311 4341 4973 0.8728 0.8634
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 1
C08
 72
hr
 1311 4473 4870 0.9184 0.9121
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 2
C08
 72
hr
 1311 4569 4961 0.9209 0.9159
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 3
C08
 72
hr
 1311 4401 4973 0.8848 0.8767