LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 KIN001-043
10
uM
LJP6
 1
C07
 72
hr
 1311 2092 4870 0.4296 0.2797
MDA-MB-231 KIN001-043
10
uM
LJP6
 2
C07
 72
hr
 1311 1989 4961 0.4009 0.2422
MDA-MB-231 KIN001-043
10
uM
LJP6
 3
C07
 72
hr
 1311 2224 4973 0.4471 0.3160
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 1311 4376 4870 0.8985 0.8901
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 1311 4398 4961 0.8864 0.8782
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 1311 4077 4973 0.8197 0.8035
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 1
D11
 72
hr
 1311 3149 4870 0.6466 0.5884
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 1311 3643 4961 0.7342 0.7027
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 1311 3144 4973 0.6321 0.5756
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 1311 2897 4870 0.5948 0.5199
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 1311 3174 4961 0.6397 0.5847
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 1311 2659 4973 0.5346 0.4441
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 1
D09
 72
hr
 1311 2325 4870 0.4774 0.3532
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 2
D09
 72
hr
 1311 2710 4961 0.5462 0.4594
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 3
D09
 72
hr
 1311 2537 4973 0.5101 0.4092
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 1311 2370 4870 0.4866 0.3669
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 1311 2637 4961 0.5315 0.4388
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 1311 2145 4973 0.4313 0.2915
MDA-MB-231 Saracatinib
10
uM
LJP6
 1
D07
 72
hr
 1311 1970 4870 0.4045 0.2397
MDA-MB-231 Saracatinib
10
uM
LJP6
 2
D07
 72
hr
 1311 2194 4961 0.4422 0.3074
MDA-MB-231 Saracatinib
10
uM
LJP6
 3
D07
 72
hr
 1311 1861 4973 0.3742 0.1995
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 1311 4575 5128 0.8921 0.8872
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 1311 4082 5100 0.8004 0.7851
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 3
B24
 72
hr
 1311 4673 5010 0.9326 0.9291
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 1
B23
 72
hr
 1311 4880 5128 0.9516 0.9502