LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 2
D18
 72
hr
 1311 5232 5100 1.0259 1.0263
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 3
D18
 72
hr
 1311 4928 5010 0.9835 0.9828
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 1
D17
 72
hr
 1311 4776 5128 0.9313 0.9289
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 2
D17
 72
hr
 1311 5230 5100 1.0255 1.0259
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 3
D17
 72
hr
 1311 4952 5010 0.9883 0.9878
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 1311 4882 5128 0.9520 0.9506
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 1311 5175 5100 1.0147 1.0150
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 1311 4458 5010 0.8897 0.8827
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 1
D15
 72
hr
 1311 4475 5128 0.8726 0.8661
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 2
D15
 72
hr
 1311 4942 5100 0.9690 0.9681
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 3
D15
 72
hr
 1311 4700 5010 0.9380 0.9348
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 1311 4938 5128 0.9629 0.9619
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 1311 5082 5100 0.9965 0.9964
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 1311 4731 5010 0.9442 0.9414
MDA-MB-231 Enzastaurin
10
uM
LJP5
 1
D13
 72
hr
 1311 5150 5128 1.0042 1.0043
MDA-MB-231 Enzastaurin
10
uM
LJP5
 2
D13
 72
hr
 1311 5111 5100 1.0022 1.0022
MDA-MB-231 Enzastaurin
10
uM
LJP5
 3
D13
 72
hr
 1311 5167 5010 1.0312 1.0320
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 1311 3372 4870 0.6924 0.6469
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 1311 3930 4961 0.7921 0.7713
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 1311 3602 4973 0.7242 0.6910
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 1311 3210 4870 0.6591 0.6046
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 1311 3341 4961 0.6734 0.6276
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 1311 3318 4973 0.6671 0.6203
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 1311 2805 4870 0.5760 0.4942
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 1311 3268 4961 0.6587 0.6090