LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SB590885
3.33
uM
LJP5
 3
L14
 72
hr
 1311 4235 5010 0.8452 0.8334
MDA-MB-231 SB590885
10
uM
LJP5
 1
L13
 72
hr
 1311 1341 5128 0.2615 0.0113
MDA-MB-231 SB590885
10
uM
LJP5
 2
L13
 72
hr
 1311 1154 5100 0.2263 -0.0633
MDA-MB-231 SB590885
10
uM
LJP5
 3
L13
 72
hr
 1311 1233 5010 0.2461 -0.0315
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 1311 3918 4870 0.8045 0.7828
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 1311 4021 4961 0.8104 0.7925
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 1311 4259 4973 0.8563 0.8450
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 1311 4094 4870 0.8406 0.8247
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 1311 4132 4961 0.8328 0.8181
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 1311 4535 4973 0.9118 0.9062
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 1311 3530 4870 0.7248 0.6872
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 1311 3807 4961 0.7673 0.7422
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 1311 3818 4973 0.7676 0.7430
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 1311 3594 4870 0.7380 0.7033
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 1311 3809 4961 0.7677 0.7427
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 1311 3703 4973 0.7445 0.7155
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 1311 3232 4870 0.6636 0.6104
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 1311 3557 4961 0.7169 0.6816
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 1311 3342 4973 0.6719 0.6264
MDA-MB-231 Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 1311 2571 4870 0.5279 0.4270
MDA-MB-231 Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 1311 2675 4961 0.5391 0.4496
MDA-MB-231 Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 1311 2546 4973 0.5119 0.4118
MDA-MB-231 PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 1311 4999 5128 0.9748 0.9742
MDA-MB-231 PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 1311 5023 5100 0.9849 0.9845
MDA-MB-231 PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 1311 5049 5010 1.0076 1.0079